Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22271773 | 0.82 | ALDH1A1 (0.35) | ALDH1A1TP53TSHR | |
| SCHEMBL852140 | 0.77 | — | — | |
| SCHEMBL852156 | 0.77 | — | — | |
| SCHEMBL852141 | 0.77 | — | — | |
| SCHEMBL12979232 | 0.75 | — | — | |
| SCHEMBL10175234 | 0.71 | — | — | |
| SCHEMBL9477308 | 0.71 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL9477319 | 0.71 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL14239242 | 0.69 | — | — | |
| SCHEMBL19013542 | 0.69 | ALDH1A1 (0.39) | ALDH1A1TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2896397-B1 | Novel compounds having inhibitory activity against sodium-dependant glucose transporter | MITSUBISHI TANABE PHARMA CORP (JP) | 2017-09-06 | — | — | EP | disclosed |
| WO-2015077866-A1 | PROTEIN KINASE INHIBITORS | PHARMASCIENCE INC. (CA) | 2015-06-04 | — | — | WO | disclosed |
| WO-2013078070-A1 | BORON-CONTAINING SMALL MOLECULES | ELI LILLY AND COMPANY (US) | 2013-05-30 | — | — | WO | disclosed |