Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.48 |
| ▸ | MARS1 | P56192 | 1/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 5/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12979602 | 0.84 | PTGER1 (0.43) | PTGER1MEN1KMT2ARAB9A | |
| SCHEMBL3712001 | 0.83 | MALT1 (0.51) | MALT1MARS1PTGER1CYP1A2MEN1 | |
| SCHEMBL24423881 | 0.79 | SMN1; SMN2 (0.50) | MALT1CYP1A2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL15579544 | 0.77 | FAAH (0.53) | MALT1MARS1CYP1A2MEN1KMT2A | |
| SCHEMBL22054628 | 0.77 | GAA (0.59) | PTGER1CYP1A2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL25413418 | 0.76 | FAAH (0.52) | MALT1KMT2AFAAHSMN1; SMN2CYP19A1 | |
| SCHEMBL27831440 | 0.75 | CA12 (0.59) | MALT1 | |
| SCHEMBL8368119 | 0.75 | ALDH1A1 (0.42) | MALT1MARS1CYP1A2MEN1KMT2A | |
| SCHEMBL8591725 | 0.75 | MALT1 (0.55) | MALT1MARS1CYP1A2MEN1KMT2A | |
| SCHEMBL20488594 | 0.75 | SMN1; SMN2 (0.54) | MALT1CYP1A2MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8703805-B2 | Modulators of LXR | EXELIXIS PATENT COMPANY LLC (US) | 2014-04-22 | — | — | US | disclosed |
| US-20100331295-A1 | MODULATORS OF LXR | EXELIXIS, INC. (US) | 2010-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100331295-A1 | MODULATORS OF LXR | NR1H2, NR1H3, NR1H4 | MALT1 2992/4885MARS1 2365/4885PTGER1 117/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.