Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 3/20 | 0.40 |
| ▸ | PLG | P00747 | 2/20 | 0.40 |
| ▸ | PLAU | P00749 | 2/20 | 0.40 |
| ▸ | PLAT | P00750 | 2/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 8/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.36 |
| ▸ | GRB2 | P62993 | 2/20 | 0.36 |
| ▸ | SRC | P12931 | 2/20 | 0.36 |
| ▸ | ZAP70 | P43403 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8906922 | 1.00 | ACACB (0.41) | ACACBF2PLGPLAUPLAT | |
| SCHEMBL10122830 | 0.89 | CYP2C19 (0.47) | ACACBF2PLGPLAUPLAT | |
| SCHEMBL888740 | 0.89 | CYP2C19 (0.47) | ACACBF2PLGPLAUPLAT | |
| SCHEMBL754142 | 0.88 | CA2 (0.46) | F2PLGPLAUPLATCA2 | |
| SCHEMBL13255953 | 0.88 | F2 (0.43) | ACACBF2PLGPLAUPLAT | |
| SCHEMBL12980056 | 0.88 | F2 (0.43) | ACACBF2PLGPLAUPLAT | |
| SCHEMBL10228106 | 0.85 | ACACB (0.41) | ACACBF2PLGPLAUPLAT | |
| SCHEMBL12281789 | 0.85 | ACACB (0.41) | ACACBF2PLGPLAUPLAT | |
| SCHEMBL10184219 | 0.85 | ACACB (0.56) | ACACBF2PLGPLAUPLAT | |
| SCHEMBL10141009 | 0.84 | MMP1 (0.35) | MMP1GRB2SRCZAP70 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010148006-A1 | HEPATITIS C VIRUS INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2010-12-23 | — | — | WO | disclosed |