Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 3/20 | 0.36 |
| ▸ | NOS3 | P29474 | 2/20 | 0.36 |
| ▸ | NOS1 | P29475 | 2/20 | 0.36 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | BHMT | Q93088 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 2/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13188067 | 1.00 | NOS2 (0.36) | NOS2NOS3NOS1ANPEPBHMT | |
| SCHEMBL1527366 | 0.81 | NOS2 (0.53) | NOS2NOS3NOS1BHMTKMT2A | |
| SCHEMBL8192425 | 0.81 | NOS2 (0.53) | NOS2NOS3NOS1BHMTKMT2A | |
| SCHEMBL3091594 | 0.81 | NOS2 (0.40) | NOS2NOS3NOS1ANPEPBHMT | |
| SCHEMBL4603896 | 0.81 | NOS2 (0.40) | NOS2NOS3NOS1ANPEPBHMT | |
| SCHEMBL1527367 | 0.81 | NOS2 (0.53) | NOS2NOS3NOS1BHMTKMT2A | |
| Hydrochloric Acid SCHEMBL11227491 | 0.79 | NOS2 (0.52) | NOS2NOS3NOS1BHMTKMT2A | |
| SCHEMBL3092715 | 0.79 | DPP4 (0.38) | NOS2NOS3NOS1ANPEPBHMT | |
| SCHEMBL12463359 | 0.77 | GABRP (0.37) | NOS2NOS3NOS1ANPEPBHMT | |
| SCHEMBL12824180 | 0.77 | GABRP (0.37) | NOS2NOS3NOS1ANPEPBHMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010148006-A1 | HEPATITIS C VIRUS INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2010-12-23 | — | — | WO | disclosed |