Known targets — ChEMBL curated mechanism
S1PR1S1PR2S1PR3S1PR4S1PR5rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 10/20 | 0.52 |
| ▸ | CA2 | P00918 | 10/20 | 0.52 |
| ▸ | CA9 | Q16790 | 8/20 | 0.52 |
| ▸ | CA12 | O43570 | 3/20 | 0.52 |
| ▸ | CA7 | P43166 | 3/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.52 |
| ▸ | CA3 | P07451 | 2/20 | 0.52 |
| ▸ | CA4 | P22748 | 2/20 | 0.52 |
| ▸ | CA6 | P23280 | 2/20 | 0.52 |
| ▸ | CA5A | P35218 | 2/20 | 0.52 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.52 |
| ▸ | RECQL | P46063 | 2/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 2/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7592784 | 1.00 | CA1 (0.52) | CA1CA2CA9CA12CA7 | |
| SCHEMBL7584886 | 1.00 | CA1 (0.52) | CA1CA2CA9CA12CA7 | |
| SCHEMBL27510902 | 1.00 | CA1 (0.52) | CA1CA2CA9CA12CA7 | |
| SCHEMBL27557255 | 1.00 | CA1 (0.52) | CA1CA2CA9CA12CA7 | |
| Ammonia Solution, Strong SCHEMBL29043301 | 0.98 | CA1 (0.50) | CA1CA2CA9CA12CA7 | |
| Ammonia Solution, Strong SCHEMBL29043303 | 0.98 | CA1 (0.50) | CA1CA2CA9CA12CA7 | |
| SCHEMBL28100266 | 0.98 | CA1 (0.50) | CA1CA2CA9CA12CA7 | |
| SCHEMBL1580314 | 0.98 | CA1 (0.50) | CA1CA2CA9CA12CA7 | |
| SCHEMBL2873558 | 0.90 | CA1 (0.57) | CA1CA2CA9CA12CA7 | |
| SCHEMBL142063 | 0.90 | CA1 (0.61) | CA1CA2CA9CA12CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110269881-A1 | METHOD FOR MANUFACTURING NATURAL RUBBER | THE YOKOHAMA RUBBER CO., LTD. (JP) | 2011-11-03 | — | — | US | disclosed |
| CN-1205360-C | Acid bath for galvanic deposition of shining gold and gold alloy layers and brightener therefor | DEGUSSA ELECTROLYTIC TECHNOLOG (DE) | 2005-06-08 | — | — | CN | disclosed |
| CN-1357060-A | Acid bath for galvanic deposition of shining gold and gold alloy layers and brightener therefor | DEGUSSA (DE) | 2002-07-03 | — | — | CN | disclosed |