Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | TACR1 | P25103 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | PPARA | Q07869 | 2/20 | 0.37 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.37 |
| ▸ | SCN1A | P35498 | 2/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.36 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12985138 | 0.86 | TACR1 (0.41) | KMT2ATACR1MEN1SMN1; SMN2KDM4E | |
| SCHEMBL12984922 | 0.80 | TACR1 (0.45) | KMT2ATACR1MEN1SMN1; SMN2KDM4E | |
| SCHEMBL5281056 | 0.80 | ALDH1A1 (0.38) | KMT2AMEN1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL5281059 | 0.80 | ALDH1A1 (0.38) | KMT2AMEN1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL12984499 | 0.74 | KMT2A (0.53) | KMT2ATACR1MEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL3963067 | 0.71 | KMT2A (0.59) | KMT2APPARGPPARA | |
| SCHEMBL12984894 | 0.70 | MEN1 (0.50) | KMT2ATACR1MEN1SMN1; SMN2KDM4E | |
| SCHEMBL12983895 | 0.69 | KMT2A (0.61) | KMT2ATACR1MEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL9901515 | 0.68 | ALDH1A1 (0.43) | KMT2ATACR1MEN1SMN1; SMN2KDM4E | |
| SCHEMBL2794043 | 0.68 | HPGD (0.39) | KMT2AMEN1KDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9414998-B2 | Preventing or ameliorating agent for pigmentation | POLA CHEMICAL INDUSTRIES INC. (JP) | 2016-08-16 | — | — | US | disclosed |
| US-20140322150-A1 | PREVENTING OR AMELIORATING AGENT FOR PIGMENTATION | POLA CHEMICAL INDUSTRIES INC. (JP) | 2014-10-30 | — | — | US | disclosed |
| EP-2514402-A1 | PROPHYLACTIC OR AMELIORATING AGENT FO PIGMENTATION | Pola Chemical Industries Inc. (JP) | 2012-10-24 | — | — | EP | disclosed |
| US-20120258063-A1 | PREVENTING OR AMELIORATING AGENT FOR PIGMENTATION | POLA CHEMICAL INDUSTRIES INC. (JP) | 2012-10-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140322150-A1 | PREVENTING OR AMELIORATING AGENT FOR PIGMENTATION | TYR, MC1R, MITF | KMT2A 1630/4885TACR1 3019/4885MEN1 2910/4885 |
| US-20120258063-A1 | PREVENTING OR AMELIORATING AGENT FOR PIGMENTATION | TYR, MC1R, MITF | KMT2A 1630/4885TACR1 3019/4885MEN1 2910/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.