Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 4/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12986835 | 1.00 | F2 (0.38) | F2DPP4LMNAPRSS1F10 | |
| SCHEMBL15610636 | 1.00 | F2 (0.38) | F2DPP4LMNAPRSS1F10 | |
| SCHEMBL12986829 | 1.00 | F2 (0.38) | F2DPP4LMNAPRSS1F10 | |
| SCHEMBL12989245 | 1.00 | F2 (0.38) | F2DPP4LMNAPRSS1F10 | |
| Hydrochloric Acid SCHEMBL15610585 | 0.99 | F2 (0.38) | F2DPP4LMNAPRSS1F10 | |
| Hydrochloric Acid SCHEMBL15610364 | 0.99 | F2 (0.38) | F2DPP4LMNAPRSS1F10 | |
| Hydrochloric Acid SCHEMBL20491373 | 0.99 | F2 (0.38) | F2DPP4LMNAPRSS1F10 | |
| Alcohol SCHEMBL20223305 | 0.96 | F2 (0.37) | F2DPP4LMNAPRSS1 | |
| Alcohol SCHEMBL15609640 | 0.96 | F2 (0.37) | F2DPP4LMNAPRSS1 | |
| SCHEMBL16774555 | 0.88 | F2 (0.37) | F2DPP4F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10385020-B2 | Process intermediates and methods for the preparation of process intermediates for the synthesis of argatroban monohydrate | LUNDBECK PHARMACEUTICALS ITALY S.P.A. (IT) | 2019-08-20 | — | — | US | claimed |
| US-20180258041-A1 | PROCESS INTERMEDIATES AND METHODS FOR THE PREPARATION OF PROCESS INTERMEDIATES FOR THE SYNTHESIS OF ARGATROBAN MONOHYDRATE | LUNDBECK PHARMACEUTICALS ITALY S.P.A. (IT) | 2018-09-13 | — | — | US | claimed |
| US-9994526-B2 | Process intermediates and methods for the preparation of process intermediates for the synthesis of argatroban monohydrate | LUNDBECK PHARMACEUTICALS ITALY S.P.A. (IT) | 2018-06-12 | — | — | US | claimed |
| US-20160347711-A1 | PROCESS INTERMEDIATES AND METHODS FOR THE PREPARATION OF PROCESS INTERMEDIATES FOR THE SYNTHESIS OF ARGATROBAN MONOHYDRATE | LUNDBECK PHARMACEUTICALS ITALY S.P.A. (IT) | 2016-12-01 | — | — | US | claimed |
| EP-2752412-B1 | Intermediates for the synthesis of Argatroban monohydrate | LUNDBECK PHARMACEUTICALS ITALY S P A (IT) | 2015-10-28 | — | — | EP | claimed |
| EP-2694493-B1 | METHOD FOR THE PREPARATION OF PROCESS INTERMEDIATES FOR THE SYNTHESIS OF ARGATROBAN MONOHYDRATE | LUNDBECK PHARMACEUTICALS ITALY S P A (IT) | 2015-06-17 | — | — | EP | claimed |
| EP-2752412-A1 | Intermediates for the synthesis of Argatroban monohydrate | Lundbeck Pharmaceuticals Italy S.p.A. (IT) | 2014-07-09 | — | — | EP | claimed |
| US-20140088310-A1 | PROCESS INTERMEDIATES AND METHODS FOR THE PREPARATION OF PROCESS INTERMEDIATES FOR THE SYNTHESIS OF ARGATROBAN MONOHYDRATE | LUNDBECK PHARMACEUTICALS ITALY S.P.A. (IT) | 2014-03-27 | — | — | US | claimed |
| US-10385020-B2 | Process intermediates and methods for the preparation of process intermediates for the synthesis of argatroban monohydrate | LUNDBECK PHARMACEUTICALS ITALY S.P.A. (IT) | 2019-08-20 | — | — | US | disclosed |
| US-10385020-B2 | Process intermediates and methods for the preparation of process intermediates for the synthesis of argatroban monohydrate | LUNDBECK PHARMACEUTICALS ITALY S.P.A. (IT) | 2019-08-20 | — | — | US | disclosed |
| US-20180258041-A1 | PROCESS INTERMEDIATES AND METHODS FOR THE PREPARATION OF PROCESS INTERMEDIATES FOR THE SYNTHESIS OF ARGATROBAN MONOHYDRATE | LUNDBECK PHARMACEUTICALS ITALY S.P.A. (IT) | 2018-09-13 | — | — | US | disclosed |
| US-20180258041-A1 | PROCESS INTERMEDIATES AND METHODS FOR THE PREPARATION OF PROCESS INTERMEDIATES FOR THE SYNTHESIS OF ARGATROBAN MONOHYDRATE | LUNDBECK PHARMACEUTICALS ITALY S.P.A. (IT) | 2018-09-13 | — | — | US | disclosed |
| US-9994526-B2 | Process intermediates and methods for the preparation of process intermediates for the synthesis of argatroban monohydrate | LUNDBECK PHARMACEUTICALS ITALY S.P.A. (IT) | 2018-06-12 | — | — | US | disclosed |
| US-9994526-B2 | Process intermediates and methods for the preparation of process intermediates for the synthesis of argatroban monohydrate | LUNDBECK PHARMACEUTICALS ITALY S.P.A. (IT) | 2018-06-12 | — | — | US | disclosed |
| US-20140088310-A1 | PROCESS INTERMEDIATES AND METHODS FOR THE PREPARATION OF PROCESS INTERMEDIATES FOR THE SYNTHESIS OF ARGATROBAN MONOHYDRATE | LUNDBECK PHARMACEUTICALS ITALY S.P.A. (IT) | 2014-03-27 | — | — | US | disclosed |
| US-20140088310-A1 | PROCESS INTERMEDIATES AND METHODS FOR THE PREPARATION OF PROCESS INTERMEDIATES FOR THE SYNTHESIS OF ARGATROBAN MONOHYDRATE | LUNDBECK PHARMACEUTICALS ITALY S.P.A. (IT) | 2014-03-27 | — | — | US | disclosed |
| EP-2694493-A1 | METHOD FOR THE PREPARATION OF PROCESS INTERMEDIATES FOR THE SYNTHESIS OF ARGATROBAN MONOHYDRATE | Lundbeck Pharmaceuticals Italy S.P.A. (IT) | 2014-02-12 | — | — | EP | disclosed |
| EP-2694493-A1 | METHOD FOR THE PREPARATION OF PROCESS INTERMEDIATES FOR THE SYNTHESIS OF ARGATROBAN MONOHYDRATE | Lundbeck Pharmaceuticals Italy S.P.A. (IT) | 2014-02-12 | — | — | EP | disclosed |
| WO-2012136504-A1 | METHOD FOR THE PREPARATION OF PROCESS INTERMEDIATES FOR THE SYNTHESIS OF ARGATROBAN MONOHYDRATE | LUNDBECK PHARMACEUTICALS ITALY S.P.A. (IT) | 2012-10-11 | — | — | WO | disclosed |
| WO-2012136504-A1 | METHOD FOR THE PREPARATION OF PROCESS INTERMEDIATES FOR THE SYNTHESIS OF ARGATROBAN MONOHYDRATE | LUNDBECK PHARMACEUTICALS ITALY S.P.A. (IT) | 2012-10-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10385020-B2 | Process intermediates and methods for the preparation of process intermediates for the synthesis of argatroban monohydrate | DHPS, MMAB, AMD1 | F2 67/4885DPP4 2022/4885LMNA 1361/4885 |
| US-20140088310-A1 | PROCESS INTERMEDIATES AND METHODS FOR THE PREPARATION OF PROCESS INTERMEDIATES FOR THE SYNTHESIS OF ARGATROBAN MONOHYDRATE | DHPS, MMAB, AMD1 | F2 67/4885DPP4 2022/4885LMNA 1361/4885 |
| US-20180258041-A1 | PROCESS INTERMEDIATES AND METHODS FOR THE PREPARATION OF PROCESS INTERMEDIATES FOR THE SYNTHESIS OF ARGATROBAN MONOHYDRATE | DHPS, MMAB, AMD1 | F2 67/4885DPP4 2022/4885LMNA 1361/4885 |
| US-20160347711-A1 | PROCESS INTERMEDIATES AND METHODS FOR THE PREPARATION OF PROCESS INTERMEDIATES FOR THE SYNTHESIS OF ARGATROBAN MONOHYDRATE | DHPS, MMAB, AMD1 | F2 67/4885DPP4 2022/4885LMNA 1361/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.