SCHEMBL1298605

SCHEMBL1298605

CCN(CC)c1ccc(C=Cc2nc3ccccc3[nH]2)cc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 10/20 0.66
▸ TP53 P04637 1/20 0.66
▸ ALDH1A1 P00352 10/20 0.64
▸ MEN1 O00255 9/20 0.64
▸ KMT2A Q03164 9/20 0.64
▸ RAB9A P51151 8/20 0.64
▸ NPC1 O15118 8/20 0.64
▸ SMN1; SMN2 Q16637 7/20 0.64
▸ KDM4E B2RXH2 6/20 0.64
▸ HPGD P15428 6/20 0.64
▸ PKM P14618 3/20 0.64
▸ HSP90AA1 P07900 1/20 0.64
▸ LMNA P02545 7/20 0.62
▸ GAA P10253 4/20 0.62
▸ GLA P06280 2/20 0.62
▸ HTT P42858 4/20 0.58
▸ NPSR1 Q6W5P4 3/20 0.58
▸ TDP1 Q9NUW8 2/20 0.58
▸ L3MBTL1 Q9Y468 2/20 0.58
▸ ATP4A P20648 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1298603 1.00 MAPT (0.66) MAPTTP53ALDH1A1MEN1KMT2A
SCHEMBL31252955 1.00 MAPT (0.66) MAPTTP53ALDH1A1MEN1KMT2A
SCHEMBL15624226 0.87 NPC1 (0.73) MAPTTP53ALDH1A1MEN1KMT2A
SCHEMBL30422072 0.85 MAPT (0.61) MAPTTP53ALDH1A1MEN1KMT2A
SCHEMBL31252953 0.85 MAPT (0.71) MAPTTP53ALDH1A1MEN1KMT2A
SCHEMBL2497906 0.85 MAPT (0.71) MAPTTP53ALDH1A1MEN1KMT2A
SCHEMBL2497904 0.85 MAPT (0.71) MAPTTP53ALDH1A1MEN1KMT2A
SCHEMBL31305038 0.84 NPC1 (0.89) MAPTTP53ALDH1A1MEN1KMT2A
SCHEMBL6482368 0.82 MAPT (0.46) MAPTTP53ALDH1A1MEN1KMT2A
SCHEMBL5572508 0.80 NPC1 (0.76) MAPTTP53ALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020162630-A1 METHOD FOR PRODUCING ORGANIC COMPOUND ダイキン工業株式会社 2020-08-13 — — WO disclosed
EP-2567954-B1 METHOD FOR INHIBITING TAU PROTEIN AGGREGATION AND TREATMENT OF ALZHEIMER'S DISEASE WITH A COMPOUND DERIVED FROM QUINOLINE UNIV CHILE (CL) 2014-06-18 — — EP disclosed
US-8575288-B2 Photocurable resin composition for forming overcoats RGB pixels black matrixes or spacers in color filter production, and color filters DAI NIPPON PRINTING CO., LTD. (JP) 2013-11-05 — — US disclosed
EP-2567954-A1 METHOD FOR INHIBITING TAU PROTEIN AGGREGATION AND TREATMENT OF ALZHEIMER'S DISEASE WITH A COMPOUND DERIVED FROM QUINOLINE Universidad De Chile (CL) 2013-03-13 — — EP disclosed
US-8198300-B2 Method for preventing tau protein aggregation and treating Alzheimer's disease with a quinoline derivative compound UNIVERSIDAD DE CHILE (CL) 2012-06-12 — — US disclosed
US-20110269793-A1 METHOD FOR PREVENTING TAU PROTEIN AGGREGATION AND TREATING ALZHEIMER'S DISEASE WITH A QUINOLINE DERIVATIVE COMPOUND UNIVERSIDAD DE CHILE (CL) 2011-11-03 — — US disclosed
US-8029877-B2 Curable resin composition, curable resin composition for forming photosensitive pattern, color filter, liquid crystal panel substrate and liquid crystal panel DAI NIPPON PRINTING CO., LTD. (JP) 2011-10-04 — — US disclosed
US-20100238388-A1 CURABLE RESIN COMPOSITION, CURABLE RESIN COMPOSITION FOR FORMING PHOTOSENSITIVE PATTERN, COLOR FILTER, LIQUID CRYSTAL PANEL SUBSTRATE AND LIQUID CRYSTAL PANEL DAI NIPPON PRINTING CO., LTD. (JP) 2010-09-23 — — US disclosed
US-7550556-B1 Highly stable resin, hardenable resin composition, production method therefor, color filter and liquid crystal panel DAI NIPPON PRINTING CO., LTD. (JP) 2009-06-23 — — US disclosed
US-7537810-B2 Curable resin composition, photosensitive pattern-forming curable resin composition, color filter, substrate for liquid crystalline panel, and liquid crystalline panel DAI NIPPON PRINTING CO., LTD. (JP) 2009-05-26 — — US disclosed
US-7399574-B2 Curable resin for photo-patterning, process for producing the same, curable resin composition, color filter, liquid crystal panel substrate, and liquid crystal panel DAI NIPPON PRINTING CO., LTD. (JP) 2008-07-15 — — US disclosed
EP-1076070-B1 Highly stable resin, hardenable resin composition, production method therefor, color filter and liquid crystal panel DAINIPPON PRINTING CO LTD (JP) 2007-04-04 — — EP disclosed
EP-1141063-B1 HIGH PHOTO-SENSITIVITY CURABLE RESIN, PHOTO-CURABLE RESIN COMPOSITION, PRODUCTION METHOD THEREOF, COLOR FILTER AND LIQUID CRYSTAL DISPLAY PANEL DAINIPPON PRINTING CO LTD (JP) 2006-12-13 — — EP disclosed
US-20060229376-A1 Curable resin composition, photosensitive pattern-forming curable resin composition,color filter, substrate for liquid crystalline panel, and liquid crystalline panel DAI NIPPON PRINTING CO., LTD. (JP) 2006-10-12 — — US disclosed
US-20030118922-A1 Curable resin for photo-patterning, process for producing the same, curable resin composition, color filter, liquid crystal panel substrate, and liquid crystal panel DAI NIPPON PRINTING CO., LTD. (JP) 2003-06-26 — — US disclosed
US-6582862-B1 Curable resin comprising polymer having main chain comprising constitutional unit having acid group and one having hydroxyl group, wherein isocyanate compound containing radical polymerizable group is bonded with acid and/or hydroxy groups DAI NIPPON PRINTING CO., LTD. (JP) 2003-06-24 — — US disclosed
EP-1141063-A1 HIGH PHOTO-SENSITIVITY CURABLE RESIN, PHOTO-CURABLE RESIN COMPOSITION, PRODUCTION METHOD THEREOF, COLOR FILTER AND LIQUID CRYSTAL DISPLAY PANEL DAI NIPPON PRINTING CO., LTD. (JP) 2001-10-10 — — EP disclosed
WO-2001027182-A1 HIGH PHOTO-SENSITIVITY CURABLE RESIN, PHOTO-CURABLE RESIN COMPOSITION, PRODUCTION METHOD THEREOF, COLOR FILTER AND LIQUID CRYSTAL DISPLAY PANEL DAI NIPPON PRINTING CO., LTD. (JP) 2001-04-19 — — WO disclosed
EP-1076070-A2 Highly stable resin, hardenable resin composition, production method therefor, color filter and liquid crystal panel DAI NIPPON PRINTING CO., LTD. (JP) 2001-02-14 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110269793-A1 METHOD FOR PREVENTING TAU PROTEIN AGGREGATION AND TREATING ALZHEIMER'S DISEASE WITH A QUINOLINE DERIVATIVE COMPOUND MAPT, PSEN2, APP MAPT 1/4885TP53 1763/4885ALDH1A1 3924/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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