Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12987053 | 0.86 | KMT2A (0.47) | KMT2AMEN1CYP2C9ALOX15CYP2C19 | |
| SCHEMBL12986889 | 0.86 | KMT2A (0.47) | KMT2AMEN1CYP2C9ALOX15CYP2C19 | |
| SCHEMBL12987782 | 0.84 | MEN1 (0.49) | KMT2AMEN1CYP2C9ALOX15CYP2C19 | |
| SCHEMBL12986566 | 0.82 | MEN1 (0.47) | KMT2AMEN1CYP2C9ALOX15CYP2C19 | |
| SCHEMBL12986930 | 0.79 | PTGS2 (0.58) | KMT2AMEN1CYP2C9ALOX15CYP2C19 | |
| SCHEMBL12988568 | 0.77 | MEN1 (0.44) | KMT2AMEN1CYP2C9ALOX15CYP2C19 | |
| SCHEMBL15655904 | 0.70 | KMT2A (0.47) | KMT2AMEN1CYP2C9ALOX15CYP2C19 | |
| SCHEMBL9377113 | 0.69 | CHIA (0.65) | KMT2AMEN1CYP2C9ALOX15CYP2C19 | |
| SCHEMBL9084228 | 0.69 | MEN1 (0.57) | KMT2AMEN1CYP2C9ALOX15CYP2C19 | |
| Hydrochloric Acid SCHEMBL9377949 | 0.69 | CHIA (0.64) | KMT2AMEN1CYP2C9ALOX15CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2693876-A1 | SUBSTITUTED METHYLFORMYL REAGENTS AND METHOD OF USING SAME TO MODIFY PHYSICOCHEMICAL AND/OR PHARMACOKINETIC PROPERTIES OF COMPOUNDS | Sphaera Pharma Pte. Ltd (SG) | 2014-02-12 | — | — | EP | claimed |
| WO-2012137225-A1 | SUBSTITUTED METHYLFORMYL REAGENTS AND METHOD OF USING SAME TO MODIFY PHYSICOCHEMICAL AND/OR PHARMACOKINETIC PROPERTIES OF COMPOUNDS | SPHAERA PHARMA PVT. LTD (IN) | 2012-10-11 | — | — | WO | claimed |