Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13728497 | 0.74 | KDM4E (0.41) | ALDH1A1MAPTPOLBHDAC2GAA | |
| SCHEMBL17934175 | 0.72 | ALDH1A1 (0.37) | ALDH1A1MAPTTSHRMEN1KMT2A | |
| SCHEMBL24732041 | 0.71 | ALDH1A1 (0.47) | ALDH1A1MAPTMEN1KMT2ATDP1 | |
| SCHEMBL4465848 | 0.70 | TP53 (0.34) | ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL30712045 | 0.70 | TDP1 (0.51) | ALDH1A1MAPTMEN1KMT2ATDP1 | |
| SCHEMBL2019104 | 0.69 | ALDH1A1 (0.48) | ALDH1A1MAPTHPGDMEN1KMT2A | |
| SCHEMBL29624960 | 0.69 | ALDH1A1 (0.48) | ALDH1A1MAPTHPGDMEN1KMT2A | |
| SCHEMBL21315683 | 0.69 | MTNR1A (0.53) | ALDH1A1TSHRMEN1KMT2AKDM4E | |
| SCHEMBL6627416 | 0.69 | ITGB1 (0.47) | ALDH1A1MAPTTSHRKMT2APOLB | |
| SCHEMBL21315658 | 0.69 | MTNR1A (0.58) | TDP1SMN1; SMN2MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2694482-A1 | WNT PATHWAY ANTAGONISTS | Siena Biotech S.p.A. (IT) | 2014-02-12 | — | — | EP | disclosed |
| WO-2012136492-A1 | WNT PATHWAY ANTAGONISTS | SIENA BIOTECH S.P.A. (IT) | 2012-10-11 | — | — | WO | disclosed |