Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
| ▸ | CDK1 | P06493 | 1/20 | 0.45 |
| ▸ | NEK2 | P51955 | 1/20 | 0.45 |
| ▸ | PLK1 | P53350 | 1/20 | 0.45 |
| ▸ | NEK7 | Q8TDX7 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | TET3 | O43151 | 4/20 | 0.41 |
| ▸ | FBXL19 | Q6PCT2 | 4/20 | 0.41 |
| ▸ | CXXC5 | Q7LFL8 | 4/20 | 0.41 |
| ▸ | KDM2B | Q8NHM5 | 4/20 | 0.41 |
| ▸ | CXXC4 | Q9H2H0 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13195341 | 0.87 | AURKA (0.44) | KMT2ACYP2C19MEN1AURKACDK1 | |
| SCHEMBL7066460 | 0.86 | KMT2A (0.70) | KMT2ACYP2C19MEN1RAB9ACYP2C9 | |
| SCHEMBL12987945 | 0.85 | HSD11B1 (0.43) | KMT2ACYP2C19AURKACDK1NEK2 | |
| SCHEMBL974153 | 0.80 | CA12 (0.51) | KMT2AMEN1AURKACDK1NEK2 | |
| SCHEMBL12987813 | 0.79 | KMT2A (0.49) | KMT2ACYP2C19MEN1RAB9ACYP2C9 | |
| SCHEMBL2221 | 0.79 | AKR1C1 (0.55) | KMT2ACYP2C19MEN1CYP2C9TSHR | |
| SCHEMBL6496131 | 0.78 | OPRM1 (0.56) | KMT2ACYP2C19MEN1CYP2C9TSHR | |
| SCHEMBL3910628 | 0.77 | AKR1C1 (0.53) | KMT2ACYP2C19MEN1CYP2C9TSHR | |
| Water SCHEMBL3910626 | 0.76 | AKR1C1 (0.52) | KMT2ACYP2C19MEN1CYP2C9TSHR | |
| SCHEMBL9966557 | 0.76 | AKR1C1 (0.68) | KMT2AMEN1TSHRSMN1; SMN2AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012138648-A1 | COMPOSITIONS AND METHODS FOR MODULATING LPA RECEPTORS | IRM LLC (BM) | 2012-10-11 | — | — | WO | disclosed |