Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 4/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.33 |
| ▸ | BCL9 | O00512 | 1/20 | 0.33 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.33 |
| ▸ | PRKCA | P17252 | 1/20 | 0.33 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.33 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20581736 | 1.00 | ALDH1A1 (0.46) | ALDH1A1LMNAMAPTMAPK1FAAH | |
| SCHEMBL15392446 | 0.84 | LMNA (0.67) | ALDH1A1LMNAMAPTMAPK1PRKCA | |
| SCHEMBL2989645 | 0.82 | ALDH1A1 (0.50) | ALDH1A1LMNAMAPTMAPK1FAAH | |
| SCHEMBL130715 | 0.82 | — | — | |
| SCHEMBL1585214 | 0.82 | ALDH1A1 (0.50) | ALDH1A1LMNAMAPTMAPK1FAAH | |
| SCHEMBL2980900 | 0.82 | ALDH1A1 (0.50) | ALDH1A1LMNAMAPTMAPK1FAAH | |
| SCHEMBL1245755 | 0.80 | ALDH1A1 (0.48) | ALDH1A1LMNAMAPTMAPK1FAAH | |
| SCHEMBL9628763 | 0.80 | ALDH1A1 (0.48) | ALDH1A1LMNAMAPTMAPK1FAAH | |
| SCHEMBL8044869 | 0.80 | ALDH1A1 (0.48) | ALDH1A1LMNAMAPTMAPK1FAAH | |
| SCHEMBL9447620 | 0.80 | ALDH1A1 (0.48) | ALDH1A1LMNAMAPTMAPK1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12006311-B2 | Compounds for use in preventing or treating cancer | FUNDACIÓ HOSPITAL UNIVERSITARI VALL D'HEBRONINSTITUT DE RECERCA (ES) | 2024-06-11 | — | — | US | disclosed |
| WO-2024083861-A1 | 1-(SULFONYL)-N-PHENYLPYRROLIDINE-2-CARBOXAMIDES DERIVATIVES AND USE THEREOF | SELABTEC SCIENCES, SLU (ES) | 2024-04-25 | — | — | WO | disclosed |
| EP-4356909-A1 | 1-(SULFONYL)-N-PHENYLPYRROLIDINE-2-CARBOXAMIDES DERIVATIVES AND USE THEREOF | Selabtec Sciences, SLU (ES) | 2024-04-24 | — | — | EP | disclosed |
| EP-3271468-B1 | DEAMINATION OF ORGANOPHOSPHORUS-NUCLEOSIDES | LABORATORIO TECNICO DE SEGURIDAD Y ESTANDARIZACION SL (ES) | 2022-12-14 | — | — | EP | disclosed |
| CN-107849594-B | Deamination of organophosphorus nucleosides | 科技学专业学院有限公司 | 2022-01-18 | — | — | CN | disclosed |
| US-20210230150-A1 | COMPOUNDS FOR USE IN PREVENTING OR TREATING CANCER | AMIRA THERAPEUTICS, S.L. (ES) | 2021-07-29 | — | — | US | disclosed |
| EP-3813832-A1 | COMPOUNDS FOR USE IN PREVENTING OR TREATING CANCER | Fundació Hospital Universitari Vall d'Hebron - Institut de Recerca (ES) | 2021-05-05 | — | — | EP | disclosed |
| US-20180066295-A1 | DEAMINATION OF ORGANOPHOSPHORUS-NUCLEOSIDES | LABORATORIO TECNICO DE SEGURIDAD Y ESTANDARIZACION, S.L.U. (ES) | 2018-03-08 | — | — | US | disclosed |
| EP-3271468-A1 | DEAMINATION OF ORGANOPHOSPHORUS-NUCLEOSIDES | Institut Univ. de Ciència i Tecnologia, S.A. (ES) | 2018-01-24 | — | — | EP | disclosed |
| EP-3128013-A1 | DEAMINATION OF ORGANOPHOSPHOROUS-NUCLEOSIDES | Institut Univ. de Ciència i Tecnologia, S.A. (ES) | 2017-02-08 | — | — | EP | disclosed |
| US-8450319-B2 | Pyrrolopyridazinone compound | UBE INDUSTRIES, LTD. (JP) | 2013-05-28 | — | — | US | disclosed |
| EP-1982986-B1 | PYRROLOPYRIDAZINONE COMPOUND AS PDE4 INHIBITOR | UBE INDUSTRIES (JP) | 2012-03-07 | — | — | EP | disclosed |
| US-20090036453-A1 | Pyrrolopyridazinone Compound | UBE INDUSTRIES, LTD. (JP) | 2009-02-05 | — | — | US | disclosed |
| EP-1982986-A1 | PYRROLOPYRIDAZINONE COMPOUND | Ube Industries, Ltd. (JP) | 2008-10-22 | — | — | EP | disclosed |
| US-5843951-A | Analgesic composition of pyrazolo(1,5-A) pyrimidines | OTSUKA PHARMACEUTICAL FACTORY INC. (JP) | 1998-12-01 | — | — | US | disclosed |
| EP-0795555-A1 | ANALGESICS | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1997-09-17 | — | — | EP | disclosed |
| US-4818429-A | FERROELECTRIC LIQUID CRYSTAL DISPLAY ELEMENTS; GOOD RESPONSE | CHISSO CORPORATION (JP) | 1989-04-04 | — | — | US | disclosed |
| EP-0260153-A2 | Cyclohexylphenylpyridazines | Chisso Corporation (JP) | 1988-03-16 | — | — | EP | disclosed |
| US-4398913-A | ALKALINE PASTES | CASSELLA AKTIENGESELLSCHAFT (DE) | 1983-08-16 | — | — | US | disclosed |
| US-4386935-A | Process for producing discharge reserve prints on textile materials with amino-azo-benzene dyes | CASSELLA AKTIENGESELLSCHAFT (DE) | 1983-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090036453-A1 | Pyrrolopyridazinone Compound | CBR3, CBR1, CYC1 | ALDH1A1 580/4885LMNA 1679/4885MAPT 4877/4885 |
| US-20210230150-A1 | COMPOUNDS FOR USE IN PREVENTING OR TREATING CANCER | UGT1A3, UGT1A1, UGT1A6 | ALDH1A1 14/4885LMNA 1451/4885MAPT 2700/4885 |
| US-12006311-B2 | Compounds for use in preventing or treating cancer | UGT1A3, UGT1A1, UGT1A6 | ALDH1A1 14/4885LMNA 1451/4885MAPT 2700/4885 |
| US-20180066295-A1 | DEAMINATION OF ORGANOPHOSPHORUS-NUCLEOSIDES | ADA, CDA, DCTD | ALDH1A1 816/4885LMNA 3127/4885MAPT 4631/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.