Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 20/20 | 0.82 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6524515 | 0.90 | HSD11B1 (1.00) | HSD11B1 | |
| SCHEMBL2636812 | 0.89 | HSD11B1 (0.78) | HSD11B1 | |
| SCHEMBL12991820 | 0.89 | HSD11B1 (0.82) | HSD11B1 | |
| SCHEMBL12991564 | 0.87 | HSD11B1 (0.83) | HSD11B1 | |
| SCHEMBL12991742 | 0.84 | HSD11B1 (0.82) | HSD11B1 | |
| SCHEMBL2636034 | 0.84 | HSD11B1 (0.72) | HSD11B1 | |
| SCHEMBL12991490 | 0.83 | HSD11B1 (0.84) | HSD11B1 | |
| SCHEMBL12991746 | 0.82 | HSD11B1 (0.83) | HSD11B1 | |
| SCHEMBL2637451 | 0.79 | HSD11B1 (1.00) | HSD11B1 | |
| SCHEMBL12792170 | 0.79 | HSD11B1 (1.00) | HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010141424-A1 | CARBAMATE AND UREA INHIBITORS OF 11BETA-HYDROXYSTEROID DEHYDROGENASE 1 | VITAE PHARMACEUTICALS, INC. (US) | 2010-12-09 | — | — | WO | disclosed |