Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 20/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12992120 | 0.89 | HSD11B1 (0.82) | HSD11B1 | |
| SCHEMBL6524515 | 0.87 | HSD11B1 (1.00) | HSD11B1 | |
| SCHEMBL2636424 | 0.87 | HSD11B1 (0.79) | HSD11B1 | |
| SCHEMBL2636417 | 0.85 | HSD11B1 (0.79) | HSD11B1 | |
| SCHEMBL2636260 | 0.85 | HSD11B1 (0.78) | HSD11B1 | |
| SCHEMBL2636421 | 0.84 | HSD11B1 (0.80) | HSD11B1 | |
| SCHEMBL2636034 | 0.81 | HSD11B1 (0.72) | HSD11B1 | |
| SCHEMBL2636288 | 0.79 | HSD11B1 (0.84) | HSD11B1 | |
| SCHEMBL12991820 | 0.79 | HSD11B1 (0.82) | HSD11B1 | |
| SCHEMBL1031163 | 0.79 | HSD11B1 (0.61) | HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2438043-A1 | CARBAMATE AND UREA INHIBITORS OF 11BETA-HYDROXYSTEROID DEHYDROGENASE 1 | Vitae Pharmaceuticals, Inc. (US) | 2012-04-11 | — | — | EP | disclosed |
| WO-2010141424-A1 | CARBAMATE AND UREA INHIBITORS OF 11BETA-HYDROXYSTEROID DEHYDROGENASE 1 | VITAE PHARMACEUTICALS, INC. (US) | 2010-12-09 | — | — | WO | disclosed |