Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.60 |
| ▸ | PRMT6 | Q96LA8 | 5/20 | 0.58 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.56 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.55 |
| ▸ | CASR | P41180 | 2/20 | 0.55 |
| ▸ | MAOB | P27338 | 2/20 | 0.51 |
| ▸ | BACE1 | P56817 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP4B1 | P13584 | 1/20 | 0.48 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29370584 | 0.89 | CHRM2 (0.68) | HTR7CHRM2CHRM1CHRM3ALDH1A1 | |
| SCHEMBL297410 | 0.89 | CHRM2 (0.68) | HTR7CHRM2CHRM1CHRM3ALDH1A1 | |
| SCHEMBL10077131 | 0.88 | PRMT6 (0.61) | HTR7PRMT6CHRM2CHRM1CHRM3 | |
| SCHEMBL24061764 | 0.83 | CHRM2 (0.60) | HTR7CHRM2CHRM1CHRM3MAOB | |
| SCHEMBL18015799 | 0.80 | MAOB (0.56) | CASRMAOBBACE1CYP1A1CYP1A2 | |
| SCHEMBL1252083 | 0.80 | PRMT6 (0.73) | HTR7PRMT6EPHX2CYP3A4 | |
| SCHEMBL196765 | 0.79 | CYP3A4 (0.73) | MAOBALDH1A1CYP1A1CYP1A2CYP2E1 | |
| SCHEMBL29489425 | 0.79 | CYP3A4 (0.73) | MAOBALDH1A1CYP1A1CYP1A2CYP2E1 | |
| SCHEMBL4937029 | 0.79 | FYN (0.56) | MAOBBACE1CYP1A1CYP1A2CYP2E1 | |
| SCHEMBL7508333 | 0.79 | MAOB (0.54) | CHRM2CHRM3CASRMAOBBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2261218-A2 | Process for preparing phenyl-, pyridinyl- or pyrimidinyl-substituted imidazoles | Eisai R&D Management Co., Ltd. (JP) | 2010-12-15 | — | — | EP | disclosed |
| EP-1757591-A1 | CINNAMIDE COMPOUND | Eisai R&D Management Co., Ltd. (JP) | 2007-02-28 | — | — | EP | disclosed |