Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.68 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.68 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | MMP13 | P45452 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.56 |
| ▸ | IDO1 | P14902 | 2/20 | 0.56 |
| ▸ | AGXT | P21549 | 2/20 | 0.56 |
| ▸ | HTR7 | P34969 | 1/20 | 0.54 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.54 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL297410 | 1.00 | CHRM2 (0.68) | CHRM2CHRM1CHRM3ALDH1A1HTT | |
| SCHEMBL24061764 | 0.93 | CHRM2 (0.60) | CHRM2CHRM1CHRM3ALDH1A1HTT | |
| SCHEMBL12993229 | 0.89 | HTR7 (0.60) | CHRM2CHRM1CHRM3ALDH1A1HTT | |
| SCHEMBL13948896 | 0.88 | ALDH1A1 (0.70) | CHRM2CHRM1CHRM3ALDH1A1HTT | |
| SCHEMBL1134127 | 0.86 | CHRM2 (0.74) | CHRM2CHRM1CHRM3ALDH1A1HTT | |
| SCHEMBL18685365 | 0.84 | CHRM2 (0.62) | CHRM2CHRM1CHRM3ALDH1A1HTT | |
| SCHEMBL7738530 | 0.84 | CHRM2 (0.62) | CHRM2CHRM1CHRM3ALDH1A1HTT | |
| SCHEMBL27962852 | 0.84 | CHRM2 (0.62) | CHRM2CHRM1CHRM3ALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL6122475 | 0.84 | CHRM2 (0.72) | CHRM2CHRM1CHRM3ALDH1A1HTT | |
| SCHEMBL2099512 | 0.83 | CHRM2 (0.66) | CHRM2CHRM1CHRM3TAAR1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4612131-A1 | NICOTINAMIDE DERIVATIVES FOR USE IN TREATING DISORDERS ASSOCIATED WITH KCNK13 ACTIVITY | Cerevance, Inc. (US) | 2025-09-10 | — | — | EP | disclosed |
| CN-119816491-A | New spirocyclohexane derivatives, pharmaceutical compositions containing them and their use as anti-apoptotic inhibitors | 法国施维雅药厂 | 2025-04-11 | — | — | CN | disclosed |
| CN-118382614-A | Novel benzyl tryptamine compounds | 瑞安神经科学公司 | 2024-07-23 | — | — | CN | disclosed |
| WO-2024095003-A1 | NICOTINAMIDE DERIVATIVES FOR USE IN TREATING DISORDERS ASSOCIATED WITH KCNK13 ACTIVITY | Cerevance, Inc. (US) | 2024-05-10 | — | — | WO | disclosed |
| CN-116829558-A | Compounds of formula (I) | 艾斯法姆生物技术股份有限公司 | 2023-09-29 | — | — | CN | disclosed |
| EP-4188933-A1 | COMPOUNDS | Esfam Biotech Pty Ltd. (AU) | 2023-06-07 | — | — | EP | disclosed |
| CN-114450277-A | Substituted pyrimidines for the treatment and prevention of hepatitis B virus infection | 豪夫迈·罗氏有限公司 | 2022-05-06 | — | — | CN | disclosed |
| WO-2022020888-A1 | COMPOUNDS | Esfam Biotech Pty Ltd (AU) | 2022-02-03 | — | — | WO | disclosed |
| WO-2022020889-A1 | METHOD OF TREATMENT OF CYTOMEGALOVIRUS | Esfam Biotech Pty Ltd (AU) | 2022-02-03 | — | — | WO | disclosed |
| WO-2022020890-A1 | TREATMENT OF VETERINARY CONDITIONS ASSOCIATED WITH CD151 | Esfam Biotech Pty Ltd (AU) | 2022-02-03 | — | — | WO | disclosed |
| WO-2022020887-A1 | TREATMENT OF CD151 RELATED DISORDERS | Esfam Biotech Pty Ltd (AU) | 2022-02-03 | — | — | WO | disclosed |
| WO-2022020891-A1 | METHODS OF PROPHYLAXIS AND TREATMENT OF CORONA VIRUS | Esfam Biotech Pty Ltd (AU) | 2022-02-03 | — | — | WO | disclosed |