Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.51 |
| ▸ | BPTF | Q12830 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10213622 | 0.84 | ADRB1 (0.43) | BPTFUSP30ALDH1A1LMNAMAPT | |
| SCHEMBL12045684 | 0.83 | MAPT (0.50) | BPTFUSP30ALDH1A1LMNAMAPT | |
| SCHEMBL27714650 | 0.83 | NOTUM (0.55) | NOTUMBPTFHRH3DRD2DRD4 | |
| SCHEMBL4396441 | 0.82 | DPP4 (0.51) | NOTUMBPTFHRH3DRD2DRD4 | |
| SCHEMBL1983505 | 0.81 | USP30 (0.40) | NOTUMBPTFUSP30ALDH1A1LMNA | |
| SCHEMBL25080722 | 0.78 | BPTF (0.43) | BPTFUSP30HTT | |
| SCHEMBL17864279 | 0.77 | NOTUM (0.56) | NOTUMDRD2DRD4ALDH1A1LMNA | |
| SCHEMBL16434855 | 0.77 | NOTUM (0.56) | NOTUMDRD2DRD4ALDH1A1LMNA | |
| SCHEMBL25080695 | 0.76 | GPR119 (0.47) | HRH3DRD2DRD4 | |
| SCHEMBL10461410 | 0.76 | NOTUM (0.46) | NOTUMBPTFHRH3USP30DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2261218-A2 | Process for preparing phenyl-, pyridinyl- or pyrimidinyl-substituted imidazoles | Eisai R&D Management Co., Ltd. (JP) | 2010-12-15 | — | — | EP | disclosed |