Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 4/20 | 0.42 |
| ▸ | MMP1 | P03956 | 3/20 | 0.42 |
| ▸ | MMP2 | P08253 | 3/20 | 0.42 |
| ▸ | MMP8 | P22894 | 3/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.40 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1908726 | 0.81 | MEN1 (0.46) | NAMPTMEN1ALDH1A1KMT2AP2RX7 | |
| SCHEMBL4573484 | 0.81 | MMP9 (0.45) | NAMPTMEN1ALDH1A1KMT2AP2RX7 | |
| SCHEMBL8838933 | 0.81 | MEN1 (0.46) | NAMPTMEN1ALDH1A1KMT2AP2RX7 | |
| SCHEMBL8351029 | 0.81 | MEN1 (0.46) | NAMPTMEN1ALDH1A1KMT2AP2RX7 | |
| SCHEMBL18539300 | 0.81 | AURKA (0.43) | NAMPTMEN1ALDH1A1KMT2AP2RX7 | |
| SCHEMBL1161663 | 0.81 | NAMPT (0.43) | NAMPTMEN1ALDH1A1KMT2AP2RX7 | |
| SCHEMBL1239662 | 0.81 | MEN1 (0.46) | NAMPTMEN1ALDH1A1KMT2AP2RX7 | |
| SCHEMBL8279734 | 0.81 | MEN1 (0.46) | NAMPTMEN1ALDH1A1KMT2AP2RX7 | |
| SCHEMBL21916831 | 0.81 | P2RX7 (0.46) | NAMPTMEN1ALDH1A1KMT2AP2RX7 | |
| SCHEMBL13181766 | 0.81 | SLC6A4 (0.44) | NAMPTMEN1ALDH1A1KMT2AP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2261218-A2 | Process for preparing phenyl-, pyridinyl- or pyrimidinyl-substituted imidazoles | Eisai R&D Management Co., Ltd. (JP) | 2010-12-15 | — | — | EP | disclosed |