Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
| ▸ | TLR2 | O60603 | 2/20 | 0.39 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | MDM4 | O15151 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 3/20 | 0.36 |
| ▸ | STS | P08842 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13039515 | 1.00 | BACE1 (0.47) | BACE1TLR2TLR1MDM2GPR119 | |
| SCHEMBL10169332 | 0.87 | BACE1 (0.42) | BACE1TLR2TLR1GPR119KDM4E | |
| SCHEMBL31340345 | 0.82 | BACE1 (0.43) | BACE1GPR119KDM4EIDO1 | |
| SCHEMBL19814665 | 0.80 | GPR119 (0.48) | GPR119KDM4ESTS | |
| SCHEMBL1219498 | 0.80 | GPR119 (0.48) | GPR119KDM4ESTS | |
| SCHEMBL3333844 | 0.80 | GPR119 (0.48) | GPR119KDM4ESTS | |
| SCHEMBL1218708 | 0.80 | GPR119 (0.48) | GPR119KDM4ESTS | |
| SCHEMBL19814663 | 0.80 | GPR119 (0.48) | GPR119KDM4ESTS | |
| SCHEMBL21197779 | 0.80 | GPR119 (0.48) | GPR119KDM4ESTS | |
| SCHEMBL1218706 | 0.80 | GPR119 (0.48) | GPR119KDM4ESTS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7858737-B2 | Heterogeneous foldamers containing α, β, and/or γ-amino acids | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2010-12-28 | — | — | US | disclosed |