Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 3/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10169332 | 0.93 | BACE1 (0.42) | BACE1USP30KMT2ALMNATHRB | |
| SCHEMBL4688249 | 0.87 | BACE1 (0.44) | BACE1USP30KMT2AGPR119IDO1 | |
| SCHEMBL5432591 | 0.87 | BACE1 (0.44) | BACE1USP30KMT2AGPR119IDO1 | |
| SCHEMBL6353989 | 0.85 | BACE1 (0.45) | BACE1USP30KMT2AGPR119KDM4E | |
| SCHEMBL31340321 | 0.85 | BACE1 (0.45) | BACE1USP30KMT2AGPR119IDO1 | |
| SCHEMBL7205505 | 0.85 | BACE1 (0.45) | BACE1USP30KMT2AGPR119KDM4E | |
| SCHEMBL6347796 | 0.84 | CPB1 (0.49) | USP30KMT2AGPR119MAPT | |
| SCHEMBL6344562 | 0.83 | BACE1 (0.46) | BACE1USP30KMT2AIDO1 | |
| SCHEMBL742949 | 0.83 | BACE1 (0.46) | BACE1USP30KMT2AIDO1 | |
| SCHEMBL30349744 | 0.83 | USP30 (0.52) | BACE1USP30KMT2AKDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4747250-A1 | KINASE INHIBITORS | The United States Of America, As Represented By The Secretary, Department of Health and Human Services (US) | 2026-05-27 | — | — | EP | disclosed |
| WO-2025019585-A1 | KINASE INHIBITORS | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2025-01-23 | — | — | WO | disclosed |