Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 3/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.40 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3964498 | 1.00 | SLC6A4 (0.42) | SLC6A4ADRA2AADRA2BADRA2CACHE | |
| SCHEMBL6950358 | 0.84 | HTR1D (0.43) | SLC6A4ADRA2AADRA2BADRA2CACHE | |
| SCHEMBL6950364 | 0.84 | HTR1D (0.43) | SLC6A4ADRA2AADRA2BADRA2CACHE | |
| SCHEMBL4621351 | 0.84 | HTR1D (0.50) | SLC6A4ADRA2AADRA2BADRA2CACHE | |
| SCHEMBL6952592 | 0.84 | HTR1D (0.50) | SLC6A4ADRA2AADRA2BADRA2CACHE | |
| SCHEMBL13534180 | 0.77 | ACHE (0.48) | SLC6A4ADRA2AADRA2BADRA2CACHE | |
| SCHEMBL12633939 | 0.77 | CA1 (0.50) | SLC6A4ADRA2AADRA2BADRA2CACHE | |
| SCHEMBL12607361 | 0.77 | CA1 (0.50) | SLC6A4ADRA2AADRA2BADRA2CACHE | |
| SCHEMBL1240585 | 0.77 | CA1 (0.50) | SLC6A4ADRA2AADRA2BADRA2CACHE | |
| SCHEMBL6959841 | 0.77 | SLC6A4 (0.50) | SLC6A4ADRA2AADRA2BADRA2CACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2261218-A2 | Process for preparing phenyl-, pyridinyl- or pyrimidinyl-substituted imidazoles | Eisai R&D Management Co., Ltd. (JP) | 2010-12-15 | — | — | EP | disclosed |
| EP-1757591-A1 | CINNAMIDE COMPOUND | Eisai R&D Management Co., Ltd. (JP) | 2007-02-28 | — | — | EP | disclosed |