Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.35 |
| ▸ | HTR2C | P28335 | 3/20 | 0.35 |
| ▸ | HTR2B | P41595 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 9/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.32 |
| ▸ | FPR2 | P25090 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 2/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12907043 | 0.92 | FPR2 (0.34) | HTR2AHTR2CHTR2BCNR2SCN9A | |
| SCHEMBL12908334 | 0.92 | CNR2 (0.37) | HTR2AHTR2CHTR2BCNR2SCN9A | |
| SCHEMBL12822882 | 0.87 | HTR2A (0.36) | HTR2AHTR2CHTR2BCNR2SCN9A | |
| SCHEMBL13586463 | 0.87 | CNR2 (0.37) | HTR2AHTR2CHTR2BCNR2SCN9A | |
| SCHEMBL13654132 | 0.87 | CNR2 (0.34) | HTR2AHTR2CHTR2BCNR2SCN9A | |
| SCHEMBL12994764 | 0.86 | OPRL1 (0.37) | HTR2AHTR2COPRL1 | |
| SCHEMBL13586558 | 0.85 | FPR2 (0.33) | HTR2AHTR2CHTR2BCNR2SCN9A | |
| SCHEMBL10302369 | 0.85 | HTR1A (0.35) | HTR2AHTR2CHTR2BCNR2SCN9A | |
| SCHEMBL13586295 | 0.84 | FPR2 (0.37) | HTR2AHTR2CHTR2BCNR2SCN9A | |
| SCHEMBL12907045 | 0.84 | CNR2 (0.35) | HTR2AHTR2CHTR2BCNR2SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2266941-A1 | TRICYCLIC LIQUID CRYSTALLINE COMPOUND HAVING LATERAL FLUORINE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | Chisso Corporation (JP) | 2010-12-29 | — | — | EP | disclosed |