Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 14/20 | 0.66 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | GHSR | Q92847 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7902550 | 0.91 | HTR2B (0.79) | HTR2B | |
| SCHEMBL1299920 | 0.89 | HTR2B (0.81) | HTR2B | |
| SCHEMBL1299373 | 0.89 | HTR2B (0.83) | HTR2BPOLBKDM4E | |
| SCHEMBL1299672 | 0.89 | HTR2B (0.83) | HTR2BPOLBKDM4E | |
| SCHEMBL1298694 | 0.89 | HTR2B (0.83) | HTR2BPOLBKDM4E | |
| SCHEMBL739141 | 0.86 | HTR2B (0.71) | HTR2BPOLBKDM4E | |
| SCHEMBL1299683 | 0.83 | HTR2B (0.87) | HTR2B | |
| SCHEMBL2520100 | 0.81 | HTR2B (0.61) | HTR2BPOLBKDM4E | |
| SCHEMBL2514536 | 0.81 | HTR2B (0.61) | HTR2BPOLBKDM4E | |
| SCHEMBL742415 | 0.81 | HTR2B (0.61) | HTR2BPOLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8609696-B2 | Serotonin 5-HT2B receptor inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-12-17 | — | — | US | disclosed |
| US-20110269742-A1 | Serotonin 5-HT2B Receptor Inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-11-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110269742-A1 | Serotonin 5-HT2B Receptor Inhibitors | HTR2B, HTR1B, HTR3B | HTR2B 1/4885POLB 1095/4885KDM4E 3720/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.