Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 11/20 | 0.71 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1298694 | 0.93 | HTR2B (0.83) | HTR2BPOLBKDM4E | |
| SCHEMBL1299373 | 0.93 | HTR2B (0.83) | HTR2BPOLBKDM4E | |
| SCHEMBL1299672 | 0.93 | HTR2B (0.83) | HTR2BPOLBKDM4E | |
| SCHEMBL2514536 | 0.89 | HTR2B (0.61) | HTR2BPOLBKDM4E | |
| SCHEMBL2520100 | 0.89 | HTR2B (0.61) | HTR2BPOLBKDM4E | |
| SCHEMBL742415 | 0.89 | HTR2B (0.61) | HTR2BPOLBKDM4E | |
| SCHEMBL1299683 | 0.87 | HTR2B (0.87) | HTR2B | |
| SCHEMBL20463440 | 0.86 | HTR2B (0.86) | HTR2B | |
| SCHEMBL1299529 | 0.86 | HTR2B (0.66) | HTR2BPOLBKDM4E | |
| SCHEMBL742064 | 0.85 | POLB (0.56) | HTR2BPOLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138168-B1 | Renin inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-03-20 | — | — | US | disclosed |