SCHEMBL12995352

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13052117	0.90	NPC1 (0.51)	NPC1RAB9AEPHX2EPHX1MEN1
	SCHEMBL12995353	0.89	NPC1 (0.50)	NPC1RAB9AEPHX2EPHX1MEN1
	SCHEMBL12995356	0.88	NPC1 (0.49)	NPC1RAB9AEPHX2EPHX1MEN1
	SCHEMBL10096450	0.88	NPC1 (0.52)	NPC1RAB9AEPHX2EPHX1MEN1
	SCHEMBL12995037	0.88	MEN1 (0.35)	NPC1RAB9AMEN1KMT2AMAPT
	SCHEMBL10096316	0.87	RAB9A (0.54)	NPC1RAB9AEPHX2EPHX1MEN1
	SCHEMBL12995358	0.86	NPC1 (0.52)	NPC1RAB9AEPHX2EPHX1MEN1
	SCHEMBL10096495	0.86	RAB9A (0.55)	NPC1RAB9AEPHX2EPHX1MEN1
	SCHEMBL14466164	0.86	NPC1 (0.50)	NPC1RAB9AEPHX2EPHX1MEN1
	SCHEMBL10096459	0.86	NPC1 (0.50)	NPC1RAB9AEPHX2EPHX1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.