Cyclooctene

Cyclooctene

SCHEMBL1299539

C1=C/CCCCCC/1.N=C(CCC(=O)OC(=O)O)OC(=O)O

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL57127 0.83 ALDH1A1 (0.35)
Ethylene Glycol SCHEMBL6129571 0.77 ALDH1A1 (0.31)
SCHEMBL7450423 0.76
SCHEMBL5775012 0.74
Cyclohexene SCHEMBL1986964 0.72
SCHEMBL3622179 0.69 ALDH1A1 (0.45)
Benzamide SCHEMBL1205193 0.69 L3MBTL1 (0.50)
SCHEMBL23042847 0.68
Cyclopentene SCHEMBL8157049 0.68
Propionic Acid SCHEMBL4983364 0.66 FFAR3 (0.56)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12030057-B2 Oligonucleotide encoded chemical libraries Plexium, Inc. (US) 2024-07-09 US disclosed
US-20230234065-A1 OLIGONUCLEOTIDE ENCODED CHEMICAL LIBRARIES Plexium, Inc. 2023-07-27 US disclosed
US-20230065224-A1 OLIGONUCLEOTIDE ENCODED CHEMICAL LIBRARIES, RELATED SYSTEMS, DEVICES, AND METHODS FOR DETECTING, ANALYZING, QUANTIFYING, AND TESTING BIOLOGICS/GENETICS PLEXIUM INC (US) 2023-03-02 US disclosed
US-11577249-B2 Oligonucleotide encoded chemical libraries Plexium, Inc. (US) 2023-02-14 US disclosed
EP-4097232-A1 OLIGONUCLEOTIDE ENCODED CHEMICAL LIBRARIES, RELATED SYSTEMS, DEVICES, AND METHODS FOR DETECTING, ANALYZING, QUANTIFYING, AND TESTING BIOLOGICS/GENETICS Plexium, Inc. (US) 2022-12-07 EP disclosed
US-20220025358-A1 OLIGONUCLEOTIDE ENCODED CHEMICAL LIBRARIES Plexium, Inc. 2022-01-27 US disclosed
US-20210394178-A1 OLIGONUCLEOTIDE ENCODED CHEMICAL LIBRARIES Plexium, Inc. 2021-12-23 US disclosed
US-11084037-B2 Oligonucleotide encoded chemical libraries Plexium, Inc. (US) 2021-08-10 US disclosed
WO-2021155040-A1 OLIGONUCLEOTIDE ENCODED CHEMICAL LIBRARIES, RELATED SYSTEMS, DEVICES, AND METHODS FOR DETECTING, ANALYZING, QUANTIFYING, AND TESTING BIOLOGICS/GENETICS Plexium, Inc. (US) 2021-08-05 WO disclosed
US-10981170-B2 Oligonucleotide encoded chemical libraries Plexium, Inc. (US) 2021-04-20 US disclosed
EP-3687687-A1 OLIGONUCLEOTIDE ENCODED CHEMICAL LIBRARIES Plexium, Inc. (US) 2020-08-05 EP disclosed
EP-3622968-A1 COMPOSITIONS AND METHODS FOR DELIVERING A SUBSTANCE TO A BIOLOGICAL TARGET The General Hospital Corporation (US) 2020-03-18 EP disclosed
EP-2361098-B1 COMPOSITIONS AND METHODS FOR DELIVERING A SUBSTANCE TO A BIOLOGICAL TARGET MASSACHUSETTS GEN HOSPITAL (US) 2019-08-28 EP disclosed
US-20190210018-A1 OLIGONUCLEOTIDE ENCODED CHEMICAL LIBRARIES Plexium, Inc. (US) 2019-07-11 US disclosed
US-20190093103-A1 OLIGONUCLEOTIDE ENCODED CHEMICAL LIBRARIES Plexium, Inc. (US) 2019-03-28 US disclosed
US-8900549-B2 Compositions and methods for delivering a substance to a biological target THE GENERAL HOSPITAL CORPORATION (US) 2014-12-02 US disclosed
US-20130302246-A1 COMPOSITIONS AND METHODS FOR DELIVERING A SUBSTANCE TO A BIOLOGICAL TARGET THE GENERAL HOSPITAL CORPORATION 2013-11-14 US disclosed
US-20110268654-A1 COMPOSITIONS AND METHODS FOR DELIVERING A SUBSTANCE TO A BIOLOGICAL TARGET THE GENERAL HOSPITAL CORPORATION (US) 2011-11-03 US disclosed
EP-2361098-A2 COMPOSITIONS AND METHODS FOR DELIVERING A SUBSTANCE TO A BIOLOGICAL TARGET The General Hospital Corporation (US) 2011-08-31 EP disclosed
WO-2010051530-A2 COMPOSITIONS AND METHODS FOR DELIVERING A SUBSTANCE TO A BIOLOGICAL TARGET THE GENERAL HOSPITAL CORPORATION (US) 2010-05-06 WO disclosed