SCHEMBL12995485

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13053079	0.93	NPC1 (0.52)	NPC1RAB9AEPHX1SMN1; SMN2CYP2C19
	SCHEMBL14468119	0.92	RAB9A (0.52)	NPC1RAB9AEPHX1SMN1; SMN2EPHX2
	SCHEMBL12995482	0.92	NPC1 (0.52)	NPC1RAB9AEPHX1SMN1; SMN2EPHX2
	SCHEMBL12995334	0.90	NPC1 (0.55)	NPC1RAB9AEPHX1SMN1; SMN2CYP2C19
	SCHEMBL12995487	0.90	NPC1 (0.52)	NPC1RAB9AEPHX1SMN1; SMN2EPHX2
	SCHEMBL12995473	0.90	NPC1 (0.49)	NPC1RAB9AEPHX1EPHX2
	SCHEMBL12995348	0.88	NPC1 (0.55)	NPC1RAB9AEPHX1SMN1; SMN2CYP2C19
	SCHEMBL12995383	0.87	NPC1 (0.56)	NPC1RAB9AEPHX1SMN1; SMN2ALDH1A1
	SCHEMBL12995209	0.87	AURKA (0.39)	NPC1RAB9ASMN1; SMN2CYP2C19CYP2C9
	SCHEMBL12995332	0.86	NPC1 (0.55)	NPC1RAB9AEPHX1SMN1; SMN2EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.