SCHEMBL1300246

SCHEMBL1300246

O=C1C[C@H](C(=O)O)N1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL690090 1.00
SCHEMBL690089 1.00
SCHEMBL6950284 0.97
SCHEMBL16467758 0.97 CAD (0.48)
Dibromoacetic Acid SCHEMBL7825550 0.87 THRB (0.42)
Dihydroorotate SCHEMBL29901858 0.84 CAD (0.43)
Dihydroorotate SCHEMBL758070 0.84 CAD (0.43)
Dihydroorotate SCHEMBL417324 0.84 CAD (0.43)
Dihydroorotate SCHEMBL121953 0.84 CAD (0.43)
SCHEMBL4453517 0.82 CAD (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3033316-B1 COMPOUNDS AND METHODS FOR IMPROVING PLANT PERFORMANCE TRIAD NAT SECURITY LLC (US) 2020-08-05 EP claimed
CN-105452198-B For improving the Compounds and methods for of plant performance 洛斯阿拉莫斯国家安全股份有限公司 2019-09-03 CN claimed
US-10117431-B2 Compounds and methods for improving plant performance LOS ALAMOS NATIONAL SECURITY, LLC (US) 2018-11-06 US claimed
US-9446992-B2 Compounds and methods for improving plant performance LOS ALAMOS NATIONAL SECURITY, LLC (US) 2016-09-20 US claimed
EP-0992491-B1 PROCESSES FOR PRODUCING AZETIDINE-2-CARBOXYLIC ACID AND INTERMEDIATES THEREOF KANEKA CORP (JP) 2003-03-05 EP claimed
EP-1187809-A1 PROCESS FOR REDUCTION OF (2R)-4-OXOAZETIDINONE-2-CARBOXYLIC ACID ABBOTT LABORATORIES (US) 2002-03-20 EP claimed
WO-2000076964-A1 PROCESS FOR REDUCTION OF (2R)-4-OXOAZETIDINONE-2-CARBOXYLIC ACID ABBOTT LABORATORIES (US) 2000-12-21 WO claimed
US-6150535-A Processes for producing azetidine-2-carboxylic acid and intermediates thereof KANEKA CORPORATION (JP) 2000-11-21 US claimed
US-6103911-A Process for reduction of (2R)-4-oxoazetidinone-2-carboxylic acid ABBOTT LABORATORIES (US) 2000-08-15 US claimed
EP-0992491-A1 PROCESSES FOR PRODUCING AZETIDINE-2-CARBOXYLIC ACID AND INTERMEDIATES THEREOF KANEKA CORPORATION (JP) 2000-04-12 EP claimed
US-11542492-B2 Ligand-directed covalent modification of protein CELGENE CAR LLC (BM) 2023-01-03 US disclosed
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed
EP-3033316-B1 COMPOUNDS AND METHODS FOR IMPROVING PLANT PERFORMANCE TRIAD NAT SECURITY LLC (US) 2020-08-05 EP disclosed
EP-3033316-B1 COMPOUNDS AND METHODS FOR IMPROVING PLANT PERFORMANCE TRIAD NAT SECURITY LLC (US) 2020-08-05 EP disclosed
US-20170218353-A1 Ligand-Directed Covalent Modification of Protein CELGENE CAR LLC (BM) 2017-08-03 US disclosed
US-4665171-A CARBACEPHALOSPORINS HARVARD UNIVERSITY (US) 1987-05-12 US disclosed
US-4636567-A CNS DISORDERS YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1987-01-13 US disclosed
US-4610821-A CENTRAL NERVOUS SYSTEM, THYROTROPIN RELEASING HORMONE YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1986-09-09 US disclosed
US-4564609-A NERVOUS SYSTEM DISORDERS YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1986-01-14 US disclosed
EP-0123444-A1 4-Substituted-2-azetidinone compound, process of producing the compounds, and medicaments containing the compounds YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) 1984-10-31 EP disclosed