Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | PRCP | P42785 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 4/20 | 0.44 |
| ▸ | DRD4 | P21917 | 4/20 | 0.44 |
| ▸ | DRD3 | P35462 | 3/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | GCGR | P47871 | 1/20 | 0.43 |
| ▸ | GIPR | P48546 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13003086 | 0.83 | GCGR (0.43) | PRCPDRD2DRD4GCGRGIPR | |
| SCHEMBL2667899 | 0.81 | GCGR (0.44) | PRCPDRD2DRD4DRD3GCGR | |
| SCHEMBL2250281 | 0.80 | GCGR (0.43) | PRCPCNR1GCGRGIPRMEN1 | |
| SCHEMBL2255802 | 0.79 | MEN1 (0.48) | GAACNR1GCGRGIPRMEN1 | |
| SCHEMBL13748634 | 0.77 | GCGR (0.46) | PRCPGCGRGIPRMEN1KMT2A | |
| SCHEMBL2251290 | 0.76 | GCGR (0.45) | PRCPGCGRGIPRMEN1KMT2A | |
| SCHEMBL2250997 | 0.76 | GCGR (0.45) | GAAPRCPGCGRGIPRMEN1 | |
| SCHEMBL2251590 | 0.75 | KMT2A (0.48) | GAACNR1GCGRGIPRMEN1 | |
| SCHEMBL2667903 | 0.75 | GCGR (0.61) | GCGRGIPR | |
| SCHEMBL2667907 | 0.74 | GCGR (0.77) | GCGRGIPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1590336-B1 | SUBSTITUTED PYRAZOLES, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE | MERCK SHARP & DOHME (US) | 2010-12-01 | — | — | EP | disclosed |