Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 7/20 | 0.43 |
| ▸ | GIPR | P48546 | 3/20 | 0.43 |
| ▸ | PRCP | P42785 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13003505 | 0.83 | GAA (0.53) | GCGRGIPRPRCPDRD4DRD2 | |
| SCHEMBL2667902 | 0.82 | GCGR (0.63) | GCGRGIPRKCNH2CYP3A4CYP2C8 | |
| SCHEMBL2667899 | 0.79 | GCGR (0.44) | GCGRGIPRPRCPDRD4HDAC1 | |
| SCHEMBL2667854 | 0.76 | GCGR (0.54) | GCGRGIPRHDAC1HDAC3HDAC4 | |
| SCHEMBL13748634 | 0.76 | GCGR (0.46) | GCGRGIPRPRCPHDAC1HDAC3 | |
| SCHEMBL2667850 | 0.75 | GCGR (0.40) | GCGRGIPRPRCPHDAC1HDAC3 | |
| SCHEMBL2667855 | 0.74 | GCGR (0.54) | GCGRGIPRHDAC1HDAC3HDAC4 | |
| SCHEMBL13749330 | 0.74 | GCGR (0.44) | GCGRGIPRMAPTMAPK1CYP2C9 | |
| SCHEMBL2667903 | 0.73 | GCGR (0.61) | GCGRGIPRKCNH2CYP3A4CYP2C8 | |
| SCHEMBL2667907 | 0.73 | GCGR (0.77) | GCGRGIPRKCNH2CYP3A4CYP2C8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1590336-B1 | SUBSTITUTED PYRAZOLES, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE | MERCK SHARP & DOHME (US) | 2010-12-01 | — | — | EP | disclosed |