Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 9/20 | 0.46 |
| ▸ | GIPR | P48546 | 5/20 | 0.46 |
| ▸ | SCD | O00767 | 1/20 | 0.45 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.41 |
| ▸ | PRCP | P42785 | 1/20 | 0.41 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2667903 | 0.88 | GCGR (0.61) | GCGRGIPRCYP2C9CYP3A4CYP2C8 | |
| SCHEMBL13748622 | 0.87 | GCGR (0.47) | GCGRGIPRCYP2C9CYP3A4CYP2C8 | |
| SCHEMBL13749330 | 0.85 | GCGR (0.44) | GCGRGIPRCYP2C9MEN1KMT2A | |
| SCHEMBL12360391 | 0.85 | GCGR (0.59) | GCGRGIPR | |
| SCHEMBL2667349 | 0.83 | GCGR (0.59) | GCGRGIPRCYP2C9CYP3A4CYP2C8 | |
| SCHEMBL2667299 | 0.78 | GCGR (0.61) | GCGRGIPR | |
| SCHEMBL2251290 | 0.78 | GCGR (0.45) | GCGRGIPRCYP2C9MEN1KMT2A | |
| SCHEMBL2667895 | 0.78 | GCGR (0.75) | GCGRGIPRCYP2C9CYP3A4CYP2C8 | |
| SCHEMBL2667902 | 0.78 | GCGR (0.63) | GCGRGIPRCYP2C9CYP3A4CYP2C8 | |
| SCHEMBL2253028 | 0.77 | GCGR (0.62) | GCGRGIPRCYP2C9CYP3A4CYP2C8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7572922-B2 | Substituted pyrazoles, compositions containing such compounds and methods of use | MERCK & CO., INC. (US) | 2009-08-11 | — | — | US | disclosed |