SCHEMBL130044

SCHEMBL130044

[CH2]Cc1ccc(OC)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 3/20 0.58
CA12 O43570 1/20 0.58
CA1 P00915 1/20 0.58
CA2 P00918 1/20 0.58
CA7 P43166 1/20 0.58
CA9 Q16790 1/20 0.58
CA14 Q9ULX7 1/20 0.58
ALDH1A1 P00352 2/20 0.58
ALOX15 P16050 2/20 0.58
TP53 P04637 1/20 0.58
CYP3A4 P08684 1/20 0.58
TSHR P16473 1/20 0.58
ALOX12 P18054 1/20 0.58
SMN1; SMN2 Q16637 1/20 0.58
AGXT P21549 2/20 0.54
LTA4H P09960 1/20 0.54
TAAR1 Q96RJ0 1/20 0.54
SLC6A4 P31645 1/20 0.50
CALM1 P0DP23 1/20 0.48
KDM4E B2RXH2 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1282941 0.84 APP (0.50) ALDH1A1TAAR1CALM1MAOB
SCHEMBL11044220 0.82 APP (0.70) IDO1CA12CA1CA2CA9
SCHEMBL216347 0.80 TAAR1 (0.61) IDO1CA12CA1CA2CA7
SCHEMBL9518961 0.80 PTGS1 (0.58) ALDH1A1ALOX15TP53CYP3A4TSHR
SCHEMBL982940 0.79 IDO1 (0.58) IDO1CA12CA1CA2CA7
SCHEMBL28860328 0.79 IDO1 (0.58) IDO1CA12CA1CA2CA7
SCHEMBL27455063 0.79 IDO1 (0.67) IDO1CA12CA1CA2CA7
SCHEMBL6291456 0.78 LTA4H (0.65) IDO1CA12CA1CA2CA7
SCHEMBL27884 0.78 LTA4H (0.81) IDO1CA12CA1CA2CA7
SCHEMBL25986524 0.78 LTA4H (0.81) IDO1CA12CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3844 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118338738-A Method for cleaning and passivating perovskite surface by using cosolvent 中国科学院化学研究所 2024-07-12 CN claimed
US-20240207253-A1 Inhibitors of CDR1 for Reversal of Azole Drug Resistance in Fungal Infections THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS 2024-06-27 US claimed
US-20240180932-A1 SUBSTITUTED RESORCYLIC ACID COMPOUNDS IN THE MANAGEMENT OF AGEING AND RELATED DISORDERS NESTLE SA (CH) 2024-06-06 US claimed
WO-2024052356-A1 INHIBITORS OF THE CERAMIDE METABOLIC PATHWAY FOR OVERCOMING IMMUNOTHERAPY RESISTANCE IN CANCER Institut National de la Santé et de la Recherche Médicale (FR) 2024-03-14 WO claimed
EP-4313017-A1 SUBSTITUTED RESORCYLIC ACID COMPOUNDS IN THE MANAGEMENT OF AGEING AND RELATED DISORDERS Société des Produits Nestlé S.A. (CH) 2024-02-07 EP claimed
CN-117343093-A Synthesis method of iron-catalyzed non-activated gem difluoro-bialkylene compound double-silicon-based 山西天宏达安医药科技有限公司 2024-01-05 CN claimed
US-20230414638-A1 SUBSTITUTED RESORCYLIC ACID COMPOUNDS AS AMPK ACTIVATOR AND USES THEREOF NESTLE SA (CH) 2023-12-28 US claimed
WO-2023222644-A1 PYRAZOLE DERIVATIVES AS STING AGONISTS F. HOFFMANN-LA ROCHE AG (CH) 2023-11-23 WO claimed
WO-2023217764-A1 NOX INHIBITORS FOR USE IN THE TREATMENT OF ALPORT SYNDROME CALLIDITAS THERAPEUTICS SUISSE SA (CH) 2023-11-16 WO claimed
WO-2023213715-A1 AMPK ACTIVATOR (CBDA) AND SGLT2 INHIBITOR FOR METABOLIC HEALTH Société des Produits Nestlé S.A. (CH) 2023-11-09 WO claimed
EP-0156224-A2 Novel benzoxathiin derivative, process for preparing them and pharmaceutical composition SUNTORY LIMITED (JP) 1985-10-02 EP claimed
US-4537890-A 2-(3,5-Substituted-2-pyridylalkylamino)-5-oxopyridylmethyl-4-pyrimidones useful as histamine H1 -antagonists SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) 1985-08-27 US claimed
EP-0090362-A2 Derivatives of cycloalka(c)pyrrole-carboxylic acids, process for their preparation, agents containing them and their use, as well as cycloalka(c)pyrrole-carboxylic acids as intermediates, and process for their preparation HOECHST AKTIENGESELLSCHAFT (DE) 1983-10-05 EP claimed
EP-0089743-A1 Novel 2,5-benzodiazocines and salts thereof having pharmaceutical activity SANWA KAGAKU KENKYUSHO CO., LTD. (JP) 1983-09-28 EP claimed
EP-0076755-A1 Acylamino-4-aza-1-adamantanes, process for their preparation and their therapeutic use ETABLISSEMENTS NATIVELLE S.A. (FR) 1983-04-13 EP claimed
US-4379788-A HYPOTENSIVES, ANTIARRHYTHMIA, B-BLOCKERS DR. KARL THOMAE GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1983-04-12 US claimed
EP-0031104-A1 Thiazolidine compounds, processes for their preparation and pharmaceutical compositions containing them SANTEN PHARMACEUTICAL CO., LTD. (JP) 1981-07-01 EP claimed
US-4234591-A Analgesic and morphine-antagonistic 9-phenyl-6,7-benzomorphans ACF CHEMIEFARMA N.V. (NL) 1980-11-18 US claimed
US-4024156-A Thiophene ethanolamines AMERICAN HOME PRODUCTS CORPORATION (US) 1977-05-17 US claimed
US-3953596-A 8-Oxa-3-azabicyclo(3.2.1)octane analgesic compositions and method of alleviating pain in animals ICI UNITED STATES INC. (US) 1976-04-27 US claimed