Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 15/20 | 0.46 |
| ▸ | CA1 | P00915 | 14/20 | 0.46 |
| ▸ | CA4 | P22748 | 8/20 | 0.46 |
| ▸ | CA12 | O43570 | 5/20 | 0.46 |
| ▸ | CA9 | Q16790 | 5/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19262245 | 0.94 | TDP1 (0.52) | CA2CA1CA4CA12CA9 | |
| SCHEMBL16518383 | 0.89 | CA1 (0.39) | CA2CA1CA4CA12CA9 | |
| SCHEMBL9393098 | 0.87 | CA1 (0.41) | CA2CA1CA4CA12CA9 | |
| SCHEMBL15159307 | 0.87 | CA1 (0.45) | CA2CA1CA4CA12CA9 | |
| SCHEMBL15159311 | 0.85 | CA1 (0.42) | CA2CA1CA4CA12CA9 | |
| Hydrochloric Acid SCHEMBL8911995 | 0.84 | CA1 (0.43) | CA2CA1CA4CA12CA9 | |
| SCHEMBL21539283 | 0.84 | TDP1 (0.56) | CA2CA1CA4CA12CA9 | |
| SCHEMBL15499780 | 0.84 | TDP1 (0.56) | CA2CA1CA4CA12CA9 | |
| SCHEMBL8719328 | 0.84 | TDP1 (0.56) | CA2CA1CA4CA12CA9 | |
| SCHEMBL9394285 | 0.84 | PAOX (0.50) | CA2CA1CA4CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8961927-B2 | Agents for magnetic imaging method | BRACCO IMAGING S.P.A. (IT) | 2015-02-24 | — | — | US | disclosed |
| US-20100311962-A1 | Agents For Magnetic Imaging Method | BRACCO IMAGING S.P.A. (IT) | 2010-12-09 | — | — | US | disclosed |
| US-7780952-B2 | Distinguish between tumor cells and normal cells using novel contrast agents that contain a Magnetic Resonance Imaging (MRI) detectable moiety bound, optionally through a spacer, to a (pseudo)nutrient such as glucose, a natural or unnatural amino acid such as agmatine, or a polyamine such as spermidine | BRACCO IMAGING SPA (IT) | 2010-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100311962-A1 | Agents For Magnetic Imaging Method | SLC19A1, SLC40A1, MPI | CA2 712/4885CA1 408/4885CA4 391/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.