Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ANPEP | P15144 | 3/20 | 0.42 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.42 |
| ▸ | DNPEP | Q9ULA0 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7257878 | 0.87 | ALDH1A1 (0.58) | ALDH1A1LMNAPKMCNR1HPGD | |
| SCHEMBL11452609 | 0.85 | ALDH1A1 (0.61) | ALDH1A1LMNAPKMCNR1HPGD | |
| SCHEMBL8847608 | 0.81 | CNR1 (0.57) | ALDH1A1LMNAPKMCNR1HPGD | |
| SCHEMBL13328249 | 0.81 | LMNA (0.60) | ALDH1A1LMNAPKMCNR1HPGD | |
| SCHEMBL24648935 | 0.79 | ALDH1A1 (0.50) | ALDH1A1LMNAPKMCNR1HPGD | |
| SCHEMBL9180556 | 0.79 | ALDH1A1 (0.50) | ALDH1A1LMNAPKMCNR1HPGD | |
| SCHEMBL17067272 | 0.79 | ALDH1A1 (0.50) | ALDH1A1LMNAPKMCNR1HPGD | |
| SCHEMBL7750825 | 0.79 | ALDH1A1 (0.55) | ALDH1A1LMNAPKMCNR1HPGD | |
| SCHEMBL22134253 | 0.79 | LMNA (0.50) | ALDH1A1LMNAPKMCNR1HPGD | |
| SCHEMBL20438643 | 0.79 | ALDH1A1 (0.50) | ALDH1A1LMNAPKMCNR1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2258400-A2 | Multivalent VLA-4 antagonists comprising polymer moieties | ELAN PHARMACEUTICALS, INC. (US) | 2010-12-08 | — | — | EP | disclosed |