Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.58 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.53 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.46 |
| ▸ | FEN1 | P39748 | 4/20 | 0.45 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.45 |
| ▸ | ABL1 | P00519 | 2/20 | 0.45 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | NNMT | P40261 | 2/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.36 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8388712 | 0.80 | ASIC3 (0.62) | ASIC3PIK3C3PIK3CDFEN1ALOX5AP | |
| SCHEMBL10293323 | 0.80 | ASIC3 (0.62) | ASIC3PIK3C3PIK3CDFEN1ALOX5AP | |
| SCHEMBL8385558 | 0.80 | ASIC3 (0.61) | ASIC3PIK3C3PIK3CDFEN1ALOX5AP | |
| SCHEMBL13533930 | 0.79 | ASIC3 (0.58) | ASIC3PIK3C3PIK3CDFEN1ALOX5AP | |
| SCHEMBL13138515 | 0.77 | ASIC3 (0.56) | ASIC3PIK3C3PIK3CDFEN1ALOX5AP | |
| SCHEMBL12961046 | 0.75 | ASIC3 (0.57) | ASIC3PIK3C3PIK3CDFEN1ALOX5AP | |
| SCHEMBL12843909 | 0.75 | ASIC3 (0.53) | ASIC3PIK3C3PIK3CDFEN1ALOX5AP | |
| SCHEMBL8388946 | 0.74 | ASIC3 (0.56) | ASIC3PIK3C3PIK3CDFEN1ALOX5AP | |
| SCHEMBL10293369 | 0.74 | NNMT (0.69) | ASIC3PIK3C3PIK3CDABL1NNMT | |
| SCHEMBL8386135 | 0.74 | ASIC3 (0.52) | ASIC3PIK3C3PIK3CDFEN1ALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633750-B1 | SYNTHESIS OF 5-SUBSTITUTED 7-AZAINDOLES AND 7-AZAINDOLINES | EISAI R&D MAN CO LTD (JP) | 2010-12-01 | — | — | EP | disclosed |