SCHEMBL13005253

SCHEMBL13005253

COCCN1/C(=C/c2ccc(O)c(C(=O)O)c2)Oc2cc(Cl)ccc21

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
DHODH Q02127 1/20 0.38
CXCL12 P48061 2/20 0.38
PTGDR2 Q9Y5Y4 1/20 0.37
STK17B O94768 2/20 0.36
HSD17B3 P37058 1/20 0.36
PTPN1 P18031 3/20 0.36
PTPN2 P17706 1/20 0.36
PTPN6 P29350 1/20 0.36
PTGS2 P35354 1/20 0.36
ALDH1A1 P00352 2/20 0.35
HPGD P15428 1/20 0.35
MAPK1 P28482 1/20 0.35
HSD17B10 Q99714 1/20 0.35
MAOB P27338 1/20 0.35
AR P10275 2/20 0.34
KDM4E B2RXH2 1/20 0.34
LMNA P02545 1/20 0.34
HNF4A P41235 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12866282 0.88 CXCL12 (0.39) CXCL12PTGDR2STK17BHSD17B3PTGS2
SCHEMBL12866241 0.84 CXCL12 (0.43) CXCL12PTGDR2STK17BHSD17B3ALDH1A1
SCHEMBL13005244 0.80 PTGDR2 (0.44) CA1CA2DHODHPTGDR2HSD17B3
SCHEMBL12880700 0.80 CA1 (0.40) CA1CA2DHODHCXCL12STK17B
SCHEMBL13005254 0.73 MEN1 (0.39) PTPN1PTPN2PTPN6PTGS2ALDH1A1
SCHEMBL12894789 0.66 CXCL12 (0.40) CXCL12STK17BMAPK1MEN1KMT2A
SCHEMBL13005251 0.66 SIGMAR1 (0.39) ALDH1A1MAPK1HSD17B10KDM4EMEN1
SCHEMBL12880691 0.65 CA1 (0.40) CA1CA2DHODHPTPN1PTPN2
SCHEMBL12866224 0.64 PTGDR2 (0.40) CXCL12PTGDR2STK17BHSD17B3ALDH1A1
5-Chlorosalicylic Acid SCHEMBL28240558 0.62 CA1 (0.92) CA1CA2PTGS2ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7851701-B2 Dye-sensitized photoelectric conversion device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2010-12-14 US disclosed