SCHEMBL12866241

SCHEMBL12866241

COCCN1/C(=C/c2ccc(O)c(OC=O)c2)Oc2cc(Cl)ccc21

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CXCL12 P48061 5/20 0.43
STK17B O94768 3/20 0.41
HSD17B3 P37058 1/20 0.38
GAA P10253 3/20 0.34
ALDH1A1 P00352 2/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
NTSR1 P30989 1/20 0.34
AR P10275 1/20 0.34
MAPK1 P28482 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
EP300 Q09472 1/20 0.33
PDE4B Q07343 1/20 0.33
JAK2 O60674 1/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
PKM P14618 1/20 0.33
RAB9A P51151 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
POLB P06746 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12866282 0.87 CXCL12 (0.39) CXCL12STK17BHSD17B3MEN1KMT2A
SCHEMBL13005253 0.84 CA1 (0.40) CXCL12STK17BHSD17B3ALDH1A1MEN1
SCHEMBL12866224 0.80 PTGDR2 (0.40) CXCL12STK17BHSD17B3GAAALDH1A1
SCHEMBL12894789 0.66 CXCL12 (0.40) CXCL12STK17BMEN1KMT2AMAPK1
SCHEMBL12880700 0.64 CA1 (0.40) CXCL12STK17BAR
SCHEMBL12866251 0.63 PRMT1 (0.42) HSD17B3GAAALDH1A1MEN1KMT2A
SCHEMBL1012820 0.60 ALDH1A1 (0.67) ALDH1A1MAPTPKMRAB9A
SCHEMBL16704450 0.58 TRPA1 (0.62) HSD17B3GAAALDH1A1MEN1KMT2A
SCHEMBL16546178 0.58 TTR (0.53) ALDH1A1MAPK1LMNAMAPT
SCHEMBL12866255 0.57 MAPT (0.55) STK17BALDH1A1MEN1KMT2AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8338700-B2 Dye-sensitized photoelectric conversion device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2012-12-25 US disclosed
US-8338701-B2 Dye-sensitized photoelectric conversion device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2012-12-25 US disclosed
US-20110030801-A1 Dye-Sensitized Photoelectric Conversion Device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2011-02-10 US disclosed
US-20110031446-A1 Dye-Sensitized Photoelectric Conversion Device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2011-02-10 US disclosed