Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 6/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1651723 | 0.85 | CHRNB2 (0.40) | MMP2CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL14018257 | 0.85 | CHRNB2 (0.40) | MMP2CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL16820690 | 0.82 | MMP2 (0.40) | MMP2CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL1651733 | 0.80 | MMP2 (0.39) | MMP2CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL13004649 | 0.76 | — | — | |
| SCHEMBL3386182 | 0.76 | — | — | |
| SCHEMBL13740486 | 0.74 | CHRNB2 (0.50) | MMP2CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL13739611 | 0.74 | CHRNB2 (0.50) | MMP2CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL13739914 | 0.74 | CHRNB2 (0.50) | MMP2CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL7517067 | 0.72 | MMP2 (0.37) | MMP2CHRNB2CHRNA4CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1858857-B1 | AZABICYCLOALKANE DERIVATIVES USEFUL AS NICOTINIC ACETYLCHOLINE RECEPTOR AGONISTS | LILLY CO ELI (US) | 2010-12-08 | — | — | EP | disclosed |