Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 2/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | RARB | P10826 | 3/20 | 0.33 |
| ▸ | RARA | P10276 | 1/20 | 0.33 |
| ▸ | RARG | P13631 | 1/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.32 |
| ▸ | OXTR | P30559 | 1/20 | 0.32 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13005279 | 0.99 | S1PR1 (0.35) | S1PR1ASAH1HTR6CNR1CNR2 | |
| SCHEMBL15274880 | 0.94 | S1PR1 (0.33) | S1PR1HTR6CNR2RARBRARA | |
| SCHEMBL13005273 | 0.94 | SIRT2 (0.38) | S1PR1RARBRARARARGSIRT2 | |
| SCHEMBL13005274 | 0.94 | MAPT (0.35) | S1PR1MAPTSMN1; SMN2 | |
| SCHEMBL13005275 | 0.93 | SIRT2 (0.39) | S1PR1ASAH1CNR1CNR2RARB | |
| SCHEMBL16474339 | 0.90 | SIRT2 (0.37) | S1PR1RARBSIRT2MAPTSMN1; SMN2 | |
| SCHEMBL13005280 | 0.88 | SIRT2 (0.37) | CNR1CNR2SIRT2MAPT | |
| SCHEMBL9914999 | 0.88 | RARB (0.39) | ASAH1CNR2RARBRARARARG | |
| SCHEMBL15693594 | 0.88 | NR4A2 (0.34) | HTR6NPC1MAPTSMN1; SMN2 | |
| SCHEMBL15693690 | 0.88 | DHODH (0.35) | HTR6NPC1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9102652-B2 | Dichroic-photochromic 2H-naphtho[1,2-b]pyran compounds and devices | ALPHAMICRON INCORPORATED (US) | 2015-08-11 | — | — | US | disclosed |
| US-20140197361-A1 | DICHROIC-PHOTOCHROMIC 2H-NAPHTHO[1,2-b]PYRAN COMPOUNDS AND DEVICES | ALPHAMICRON INCORPORATED (US) | 2014-07-17 | — | — | US | disclosed |
| US-20100324296-A1 | DICHROIC-PHOTOCHROMIC COMPOUNDS AND DEVICES | ALPHAMICRON INCORPORATED | 2010-12-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140197361-A1 | DICHROIC-PHOTOCHROMIC 2H-NAPHTHO[1,2-b]PYRAN COMPOUNDS AND DEVICES | NR0B2, NR0B1, DHCR24 | S1PR1 630/4885ASAH1 4030/4885HTR6 95/4885 |
| US-20100324296-A1 | DICHROIC-PHOTOCHROMIC COMPOUNDS AND DEVICES | NR0B2, NR0B1, NR2E3 | S1PR1 807/4885ASAH1 4072/4885HTR6 682/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.