Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | RARB | P10826 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13005275 | 0.99 | SIRT2 (0.39) | SIRT2S1PR1RARBKDM4EALDH1A1 | |
| SCHEMBL16474339 | 0.96 | SIRT2 (0.37) | SIRT2S1PR1RARBKDM4EALDH1A1 | |
| SCHEMBL13005280 | 0.94 | SIRT2 (0.37) | SIRT2MAPT | |
| SCHEMBL13005281 | 0.94 | S1PR1 (0.35) | SIRT2S1PR1RARBDGAT1MAPT | |
| SCHEMBL13005279 | 0.93 | S1PR1 (0.35) | SIRT2S1PR1RARBDGAT1MAPT | |
| SCHEMBL16474337 | 0.93 | SIRT2 (0.36) | SIRT2S1PR1KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL13005285 | 0.92 | DGAT1 (0.33) | SIRT2S1PR1RARBKDM4EALDH1A1 | |
| SCHEMBL18971203 | 0.92 | ALDH1A1 (0.39) | SIRT2KDM4EALDH1A1L3MBTL1LMNA | |
| SCHEMBL18961305 | 0.91 | SIRT2 (0.36) | SIRT2S1PR1 | |
| SCHEMBL15277649 | 0.91 | ALDH1A1 (0.36) | SIRT2KDM4EALDH1A1L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9771518-B2 | Photo responsive material and optical device | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2017-09-26 | — | — | US | disclosed |
| US-20170166814-A1 | PHOTO RESPONSIVE MATERIAL AND OPTICAL DEVICE | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2017-06-15 | — | — | US | disclosed |
| US-9200203-B2 | Phototropic liquid crystal material and processes | ALPHAMICRON INCORPORATED (US) | 2015-12-01 | — | — | US | disclosed |
| US-9102652-B2 | Dichroic-photochromic 2H-naphtho[1,2-b]pyran compounds and devices | ALPHAMICRON INCORPORATED (US) | 2015-08-11 | — | — | US | disclosed |
| US-20140197361-A1 | DICHROIC-PHOTOCHROMIC 2H-NAPHTHO[1,2-b]PYRAN COMPOUNDS AND DEVICES | ALPHAMICRON INCORPORATED (US) | 2014-07-17 | — | — | US | disclosed |
| US-20130248350-A1 | PHOTOTROPIC LIQUID CRYSTAL MATERIAL AND PROCESSES | ALPHAMICRON INCORPORATED | 2013-09-26 | — | — | US | disclosed |
| US-20100324296-A1 | DICHROIC-PHOTOCHROMIC COMPOUNDS AND DEVICES | ALPHAMICRON INCORPORATED | 2010-12-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140197361-A1 | DICHROIC-PHOTOCHROMIC 2H-NAPHTHO[1,2-b]PYRAN COMPOUNDS AND DEVICES | NR0B2, NR0B1, DHCR24 | SIRT2 1036/4885S1PR1 630/4885RARB 23/4885 |
| US-20100324296-A1 | DICHROIC-PHOTOCHROMIC COMPOUNDS AND DEVICES | NR0B2, NR0B1, NR2E3 | SIRT2 1416/4885S1PR1 807/4885RARB 11/4885 |
| US-20170166814-A1 | PHOTO RESPONSIVE MATERIAL AND OPTICAL DEVICE | LSM12, MYB, CRY1 | SIRT2 4745/4885S1PR1 3205/4885RARB 168/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.