Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.46 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 4/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13005630 | 0.91 | CALM1 (0.40) | CALM1CAMKK2KDM4EALDH1A1TSHR | |
| SCHEMBL13005633 | 0.90 | CALM1 (0.40) | CALM1CAMKK2KDM4EALDH1A1TSHR | |
| SCHEMBL13061083 | 0.86 | CALM1 (0.49) | CALM1CAMKK2KDM4EALDH1A1TSHR | |
| SCHEMBL13005634 | 0.86 | CALM1 (0.42) | CALM1CAMKK2KDM4EALDH1A1TSHR | |
| SCHEMBL13005440 | 0.86 | CALM1 (0.59) | CALM1CAMKK2KDM4EALDH1A1TSHR | |
| SCHEMBL13005546 | 0.85 | CALM1 (0.47) | CALM1CAMKK2KDM4EALDH1A1TSHR | |
| SCHEMBL13005713 | 0.84 | CALM1 (0.46) | CALM1CAMKK2KDM4EALDH1A1TSHR | |
| SCHEMBL13005676 | 0.83 | CALM1 (0.45) | CALM1CAMKK2KDM4EALDH1A1TSHR | |
| SCHEMBL13005649 | 0.83 | CALM1 (0.45) | CALM1CAMKK2KDM4EALDH1A1TSHR | |
| SCHEMBL13005661 | 0.83 | CALM1 (0.45) | CALM1CAMKK2KDM4EALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7851637-B2 | Compounds and methods for inhibiting the interaction of BCL proteins with binding partners | INFINITY PHARMACEUTICALS, INC. (US) | 2010-12-14 | — | — | US | disclosed |