Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7885536 | 0.78 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL13064463 | 0.77 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL171508 | 0.75 | ALDH1A1 (0.55) | ALDH1A1 | |
| SCHEMBL7995892 | 0.73 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL12184466 | 0.66 | — | — | |
| SCHEMBL10574474 | 0.65 | ALDH1A1 (0.43) | ALDH1A1 | |
| SCHEMBL8208648 | 0.62 | — | — | |
| SCHEMBL8227457 | 0.60 | — | — | |
| SCHEMBL15910079 | 0.60 | ALDH1A1 (0.46) | ALDH1A1 | |
| SCHEMBL13397357 | 0.60 | ALDH1A1 (0.46) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1784396-B1 | PYRAZOLE-SUBSTITUTED AMINOHETEROARYL COMPOUNDS AS PROTEIN KINASE INHIBITORS | PFIZER (US) | 2010-12-22 | — | — | EP | disclosed |
| WO-2009152920-A1 | 3-(3-PYRIMIDIN-2-YL-BENZYL)-[1,2,4]TRIAZOLO[4,3-B]PYRIDAZINE DERIVATIVES AS MET KINASE INHIBITORS | MERCK PATENT GMBH (DE) | 2009-12-23 | — | — | WO | disclosed |
| WO-2008012524-A1 | SUBSTITUTED ANILINE DERIVATIVES | UCB PHARMA S.A. (BE) | 2008-01-31 | — | — | WO | disclosed |