Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7885536 | 0.85 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL13005648 | 0.77 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL171508 | 0.71 | ALDH1A1 (0.55) | ALDH1A1 | |
| SCHEMBL7995892 | 0.69 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL12184466 | 0.62 | — | — | |
| SCHEMBL10574474 | 0.61 | ALDH1A1 (0.43) | ALDH1A1 | |
| SCHEMBL8208648 | 0.59 | — | — | |
| SCHEMBL14846411 | 0.57 | — | — | |
| SCHEMBL8227457 | 0.57 | — | — | |
| SCHEMBL15910079 | 0.57 | ALDH1A1 (0.46) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010132487-A1 | CRYSTALLINE FORMS OF (S)-7-([1,2,4]TRIAZOLO[1,5-a]PYRIDIN-6-YL)-4-(3,4-DICHLOROHPHENYL)-1,2,3,4-TETRAHYDROISOQUINOLINE AND USE THEREOF | BRISTOL-MYERS SQUIBB COMPANY (US) | 2010-11-18 | — | — | WO | disclosed |
| WO-2010132442-A1 | 7-([1,2,4,]TRIAZOLO[1,5,-A]PYRIDIN-6-YL)-4-(3,4-DICHLOROPHENYL)-1,2,3,4- TETRAHYDROISOQUINOLINE AND USE THEREOF | ALBANY MOLECULAR RESERCH, INC. (US) | 2010-11-18 | — | — | WO | disclosed |