Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.38 |
| ▸ | FDPS | P14324 | 3/20 | 0.38 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.36 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28030015 | 0.79 | OPRM1 (0.44) | OPRM1SMPD1FDPSSPHK1LMNA | |
| SCHEMBL28142906 | 0.79 | OPRM1 (0.44) | OPRM1SMPD1FDPSSPHK1LMNA | |
| SCHEMBL5698215 | 0.77 | LMNA (0.42) | OPRM1FDPSSPHK1LMNADNM1 | |
| SCHEMBL14762412 | 0.74 | OPRM1 (0.48) | OPRM1SMPD1FDPSSPHK1LMNA | |
| SCHEMBL14763014 | 0.74 | OPRM1 (0.48) | OPRM1SMPD1FDPSSPHK1LMNA | |
| SCHEMBL15241739 | 0.74 | OPRM1 (0.48) | OPRM1FDPSSPHK1LMNADNM1 | |
| SCHEMBL15178483 | 0.74 | OPRM1 (0.48) | OPRM1FDPSSPHK1LMNADNM1 | |
| SCHEMBL30139997 | 0.74 | OPRM1 (0.48) | OPRM1SMPD1FDPSSPHK1LMNA | |
| SCHEMBL3518176 | 0.74 | OPRM1 (0.48) | OPRM1SMPD1FDPSSPHK1LMNA | |
| SCHEMBL31091582 | 0.74 | OPRM1 (0.42) | OPRM1FDPSSPHK1LMNADNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1427750-B1 | MODIFIED TRANSFERRIN FUSION PROTEINS | BIOREXIS PHARMACEUTICAL CORP (US) | 2010-12-08 | — | — | EP | disclosed |