Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | PROKR1 | Q8TCW9 | 6/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | BCL9 | O00512 | 1/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3761983 | 1.00 | ALDH1A1 (0.51) | ALDH1A1MAPTLMNAHPGDHIF1A | |
| SCHEMBL3761979 | 0.83 | ALDH1A1 (0.44) | ALDH1A1MAPTLMNAHPGDHIF1A | |
| SCHEMBL414423 | 0.82 | ALDH1A1 (0.49) | ALDH1A1LMNAHPGDHIF1ARAB9A | |
| SCHEMBL414422 | 0.82 | ALDH1A1 (0.49) | ALDH1A1LMNAHPGDHIF1ARAB9A | |
| SCHEMBL3771429 | 0.80 | CNR1 (0.41) | ALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL3772381 | 0.80 | CNR1 (0.41) | ALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL13006068 | 0.77 | MAPT (0.50) | ALDH1A1MAPTLMNAHPGDHIF1A | |
| SCHEMBL3775072 | 0.77 | MAPT (0.50) | ALDH1A1MAPTLMNAHPGDHIF1A | |
| SCHEMBL381249 | 0.76 | ALDH1A1 (0.49) | ALDH1A1LMNAHPGDHIF1ARAB9A | |
| SCHEMBL381248 | 0.76 | ALDH1A1 (0.49) | ALDH1A1LMNAHPGDHIF1ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170320870-A1 | COMPOUNDS | MEDICAL RESEARCH COUNCIL TECHNOLOGY (GB) | 2017-11-09 | — | — | US | disclosed |
| US-20170320870-A1 | COMPOUNDS | MEDICAL RESEARCH COUNCIL TECHNOLOGY (GB) | 2017-11-09 | — | — | US | disclosed |
| EP-2408772-B1 | COMPOUNDS | MEDICAL RES COUNCIL TECHNOLOGY (GB) | 2015-07-01 | — | — | EP | disclosed |
| US-20100317646-A1 | COMPOUNDS | MEDICAL RESEARCH COUNCIL TECHNOLOGY (GB) | 2010-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170320870-A1 | COMPOUNDS | CBR3, CNR1, HCAR3 | ALDH1A1 2980/4885MAPT 4568/4885LMNA 2925/4885 |
| US-20100317646-A1 | COMPOUNDS | CBR3, CNR1, HCAR3 | ALDH1A1 2975/4885MAPT 4576/4885LMNA 2870/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.