Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.40 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.40 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.40 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.40 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 5/20 | 0.36 |
| ▸ | RAB9A | P51151 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12364936 | 0.95 | ALDH1A1 (0.43) | ALDH1A1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL30884776 | 0.80 | ALDH1A1 (0.43) | ALDH1A1BAZ2BHPGDMEN1LMNA | |
| SCHEMBL25082660 | 0.80 | ALDH1A1 (0.43) | ALDH1A1BAZ2BHPGDMEN1LMNA | |
| SCHEMBL30884764 | 0.78 | ALDH1A1 (0.42) | ALDH1A1BAZ2BHPGDMEN1LMNA | |
| SCHEMBL25082654 | 0.78 | ALDH1A1 (0.42) | ALDH1A1BAZ2BHPGDMEN1LMNA | |
| SCHEMBL12365901 | 0.77 | MTNR1A (0.45) | ALDH1A1HPGDMEN1LMNAKMT2A | |
| SCHEMBL9288475 | 0.76 | ALDH1A1 (0.47) | ALDH1A1BAZ2BHPGDMEN1LMNA | |
| SCHEMBL19995829 | 0.76 | ALDH1A1 (0.47) | ALDH1A1BAZ2BHPGDMEN1LMNA | |
| SCHEMBL30567324 | 0.74 | ALDH1A1 (0.68) | ALDH1A1MEN1LMNATHRATHRB | |
| SCHEMBL1613763 | 0.74 | ALDH1A1 (0.68) | ALDH1A1MEN1LMNATHRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1866292-B1 | TRICYCLIC 1,2,4-TRIAZINE OXIDES AND COMPOSITIONS THEREFROM FOR THERAPEUTIC USE IN CANCER TREATMENTS | AUCKLAND UNISERVICES LTD (NZ) | 2010-12-15 | — | — | EP | disclosed |