Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | METAP1 | P53582 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 4/20 | 0.31 |
| ▸ | MAOB | P27338 | 4/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.31 |
| ▸ | PRKDC | P78527 | 1/20 | 0.31 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.30 |
| ▸ | CCR1 | P32246 | 2/20 | 0.30 |
| ▸ | CCR5 | P51681 | 2/20 | 0.30 |
| ▸ | CCR8 | P51685 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | ALPL | P05186 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13006468 | 0.94 | HSP90AA1 (0.33) | MAPK14MCL1METAP1IRAK4MAPT | |
| SCHEMBL13006466 | 0.89 | MAPT (0.38) | MAPK14IRAK4MAPTMAOAMAOB | |
| SCHEMBL12011852 | 0.87 | MAPK14 (0.32) | MAPK14MCL1METAP1MAPTMAOA | |
| SCHEMBL13006431 | 0.87 | CYP11B1 (0.37) | MCL1METAP1IRAK4MAPTMAOA | |
| SCHEMBL4561522 | 0.86 | MAOA (0.37) | MAOAMAOBACHEMKNK1MKNK2 | |
| SCHEMBL4562405 | 0.86 | MAOA (0.37) | MAOAMAOBACHEMKNK1MKNK2 | |
| SCHEMBL13006461 | 0.86 | MAPT (0.40) | MAPK14IRAK4MAPTMAOAMAOB | |
| SCHEMBL13006448 | 0.85 | IRAK4 (0.36) | MCL1METAP1IRAK4MAPTMAOA | |
| SCHEMBL13006418 | 0.85 | MCL1 (0.40) | MCL1IRAK4MAPTMAOAMAOB | |
| SCHEMBL13006544 | 0.85 | MAOA (0.31) | MAOAMAOBACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2246351-B1 | COMPOUND HAVING PYRIDOINDOLE RING STRUCTURE BONDED WITH SUBSTITUTED PYRIDYL GROUP, AND ORGANIC ELECTROLUMINESCENT DEVICE | HODOGAYA CHEMICAL CO LTD (JP) | 2015-05-06 | — | — | EP | disclosed |
| US-8624228-B2 | Compound having pyridoindole ring structure bonded with substituted pyridyl group, and organic electroluminescent device | HODOGAYA CHEMICAL CO., LTD. (JP) | 2014-01-07 | — | — | US | disclosed |
| US-8624228-B2 | Compound having pyridoindole ring structure bonded with substituted pyridyl group, and organic electroluminescent device | HODOGAYA CHEMICAL CO., LTD. (JP) | 2014-01-07 | — | — | US | disclosed |
| US-20100308322-A1 | COMPOUND HAVING PYRIDOINDOLE RING STRUCTURE BONDED WITH SUBSTITUTED PYRIDYL GROUP, AND ORGANIC ELECTROLUMINESCENT DEVICE | Hodogaya Chemical Co,. Ltd. (JP) | 2010-12-09 | — | — | US | disclosed |
| US-20100308322-A1 | COMPOUND HAVING PYRIDOINDOLE RING STRUCTURE BONDED WITH SUBSTITUTED PYRIDYL GROUP, AND ORGANIC ELECTROLUMINESCENT DEVICE | Hodogaya Chemical Co,. Ltd. (JP) | 2010-12-09 | — | — | US | disclosed |
| EP-2246351-A1 | COMPOUND HAVING PYRIDOINDOLE RING STRUCTURE BONDED WITH SUBSTITUTED PYRIDYL GROUP, AND ORGANIC ELECTROLUMINESCENT DEVICE | Hodogaya Chemical Co., Ltd. (JP) | 2010-11-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100308322-A1 | COMPOUND HAVING PYRIDOINDOLE RING STRUCTURE BONDED WITH SUBSTITUTED PYRIDYL GROUP, AND ORGANIC ELECTROLUMINESCENT DEVICE | KCNH3, KCNH2, PRDM9 | MAPK14 3179/4885MCL1 4204/4885METAP1 4452/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.