Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.39 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28594144 | 0.94 | ACE2 (0.55) | ACE2CA2CA1GPR84HAO1 | |
| SCHEMBL1300587 | 0.86 | TSHR (0.44) | ACE2CA1GPR84HAO1 | |
| SCHEMBL31243245 | 0.83 | MAPK1 (0.37) | ACE2MAPK1CA1MAPT | |
| SCHEMBL31243242 | 0.83 | MAPK1 (0.37) | ACE2MAPK1CA1MAPT | |
| SCHEMBL301256 | 0.82 | GPR84 (0.52) | ACE2CA2MAPK1GPR84MAPT | |
| SCHEMBL4435960 | 0.82 | GPR84 (0.52) | ACE2CA2MAPK1GPR84MAPT | |
| SCHEMBL905453 | 0.82 | GPR84 (0.52) | ACE2CA2MAPK1GPR84MAPT | |
| Hydrochloric Acid SCHEMBL27778084 | 0.80 | GPR84 (0.50) | ACE2CA2MAPK1GPR84MAPT | |
| SCHEMBL28055317 | 0.80 | GPR84 (0.50) | ACE2CA2MAPK1GPR84MAPT | |
| SCHEMBL28716932 | 0.79 | ACE2 (0.47) | ACE2CA2MAPK1CA1GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9023636-B2 | Microorganisms and methods for the biosynthesis of propylene | GENOMATICA, INC. (US) | 2015-05-05 | — | — | US | disclosed |
| US-8617862-B2 | Microorganisms for producing propylene and methods related thereto | GENOMATICA, INC. (US) | 2013-12-31 | — | — | US | disclosed |
| EP-2563926-A1 | MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF PROPYLENE | Genomatica, Inc. (US) | 2013-03-06 | — | — | EP | disclosed |
| US-20120329119-A1 | MICROORGANISMS FOR PRODUCING PROPYLENE AND METHODS RELATED THERETO | GENOMATICA, INC. | 2012-12-27 | — | — | US | disclosed |
| WO-2011137198-A1 | MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF PROPYLENE | GENOMATICA, INC. (US) | 2011-11-03 | — | — | WO | disclosed |
| US-20110269204-A1 | MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF PROPYLENE | AGAIN BIO APS (DK) | 2011-11-03 | — | — | US | disclosed |