SCHEMBL13006706

SCHEMBL13006706

Cc1ccc2c3c(cccc13)C(=O)c1ccccc1-2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 1.00
MAPT P10636 4/20 1.00
PABPC1 P11940 3/20 1.00
KDM4E B2RXH2 2/20 1.00
CYP3A4 P08684 5/20 0.55
DNMT1 P26358 2/20 0.55
CASP1 P29466 1/20 0.55
CASP7 P55210 1/20 0.55
CYP1A2 P05177 4/20 0.53
ALDH1A1 P00352 3/20 0.49
HBB P68871 2/20 0.49
CYP2C9 P11712 2/20 0.49
TYMS P04818 1/20 0.47
ELANE P08246 3/20 0.47
NPC1 O15118 2/20 0.47
MAPK1 P28482 2/20 0.47
RAB9A P51151 2/20 0.47
TSHR P16473 2/20 0.47
CASP3 P42574 1/20 0.47
SENP7 Q9BQF6 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18288098 1.00 SMN1; SMN2 (1.00) SMN1; SMN2MAPTPABPC1KDM4ECYP3A4
SCHEMBL12293691 0.88 MAPT (0.79) SMN1; SMN2MAPTPABPC1KDM4ECYP3A4
SCHEMBL22635004 0.88 PABPC1 (0.78) SMN1; SMN2MAPTPABPC1KDM4ECYP3A4
SCHEMBL14985691 0.86 MAPT (0.76) SMN1; SMN2MAPTPABPC1KDM4ECYP3A4
SCHEMBL10028838 0.86 MAPT (0.76) SMN1; SMN2MAPTPABPC1KDM4ECYP3A4
SCHEMBL29456701 0.84 PABPC1 (0.72) SMN1; SMN2MAPTPABPC1KDM4ECYP3A4
SCHEMBL13045522 0.84 PABPC1 (0.72) SMN1; SMN2MAPTPABPC1KDM4ECYP3A4
SCHEMBL15500320 0.81 MAPT (0.68) SMN1; SMN2MAPTPABPC1KDM4ECYP3A4
SCHEMBL18462559 0.81 MAPT (0.68) SMN1; SMN2MAPTPABPC1KDM4ECYP3A4
SCHEMBL17589321 0.79 KDM4E (0.66) SMN1; SMN2MAPTPABPC1KDM4ECYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160202560-A1 PHOTO-ALIGNMENT MATERIAL AND PHOTO-ALIGNMENT METHOD TOKYO INSTITUTE OF TECHNOLOGY (JP) 2016-07-14 US disclosed
US-20150357575-A1 AMINE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-12-10 US disclosed
US-20100310975-A1 Electrophotographic Photoreceptor, And Image Forming Apparatus And Process Cartridge Therefor Using The Photoreceptor RICOH COMPANY, LTD. (JP) 2010-12-09 US disclosed