Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PABPC1 | P11940 | 4/20 | 0.72 |
| ▸ | MAPT | P10636 | 4/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.63 |
| ▸ | CASP1 | P29466 | 3/20 | 0.63 |
| ▸ | DNMT1 | P26358 | 2/20 | 0.63 |
| ▸ | CASP7 | P55210 | 2/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.54 |
| ▸ | HBB | P68871 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | CDC25B | P30305 | 1/20 | 0.52 |
| ▸ | CRHBP | P24387 | 1/20 | 0.52 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.52 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.52 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29456701 | 1.00 | PABPC1 (0.72) | PABPC1MAPTSMN1; SMN2KDM4ECYP3A4 | |
| SCHEMBL24334669 | 0.88 | MAPT (0.64) | PABPC1MAPTSMN1; SMN2KDM4ECYP3A4 | |
| SCHEMBL20835013 | 0.86 | MAPT (0.66) | PABPC1MAPTSMN1; SMN2KDM4ECYP3A4 | |
| SCHEMBL1983882 | 0.84 | PABPC1 (0.64) | PABPC1MAPTSMN1; SMN2KDM4ECYP3A4 | |
| SCHEMBL18288098 | 0.84 | SMN1; SMN2 (1.00) | PABPC1MAPTSMN1; SMN2KDM4ECYP3A4 | |
| SCHEMBL29698127 | 0.84 | PABPC1 (0.64) | PABPC1MAPTSMN1; SMN2KDM4ECYP3A4 | |
| SCHEMBL13006706 | 0.84 | SMN1; SMN2 (1.00) | PABPC1MAPTSMN1; SMN2KDM4ECYP3A4 | |
| SCHEMBL16582580 | 0.84 | KEAP1 (0.78) | PABPC1MAPTSMN1; SMN2KDM4ECYP3A4 | |
| SCHEMBL17322323 | 0.84 | PABPC1 (0.64) | PABPC1MAPTSMN1; SMN2KDM4ECYP3A4 | |
| SCHEMBL29907914 | 0.84 | PABPC1 (0.64) | PABPC1MAPTSMN1; SMN2KDM4ECYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7838126-B2 | Organic electronic devices | MERCK PATENT GMBH (DE) | 2010-11-23 | — | — | US | disclosed |
| US-7838126-B2 | Organic electronic devices | MERCK PATENT GMBH (DE) | 2010-11-23 | — | — | US | disclosed |
| US-20070164273-A1 | Organic electronic devices | MERCK PATENT GMBH (DE) | 2007-07-19 | — | — | US | disclosed |
| US-20070164273-A1 | Organic electronic devices | MERCK PATENT GMBH (DE) | 2007-07-19 | — | — | US | disclosed |